Somatostatin-28 (1-14)

发表于由

Somatostatin-28 (1-14);

Somatostatin-28 (1-14) 是神经肽生长抑素-28的N-末端片段。

Somatostatin-28 (1-14)amp;;

Somatostatin-28 (1-14) Chemical Structure

CAS No. : 79243-10-0

规格 价格 是否有货
1 mg ￥1800 询问价格 货期
5 mg ￥7200 询问价格 货期
10 mg ￥11000 询问价格 货期

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生物活性

Somatostatin-28 (1-14) is an N-terminal fragment of the neuropeptide somatostatin-28.

体外研究
(In Vitro)

The tetradecapeptide hormone somatostatin arises from proteolytic processing of a large precursor, preprosomatostatin[1]. Somatostatin-28 (1-14) has been used to produce antibodies selective for somatostatin-28 that do not bind to the C-terminal fragment somatostatin-14[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1528.71

Formula

C61H105N23O21S
CAS 号

79243-10-0
Sequence

Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys
Sequence Shortening

SANSNPAMAPRERK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Goodman RH, et al. Rat pre-prosomatostatin. Structure and processing by microsomal membranes. J Biol Chem. 1983 May 10;258(9):5570-3.

    [2]. Zeggari M, et al. Co-purification of a protein tyrosine phosphatase with activated somatostatin receptors from rat pancreatic acinar membranes. Biochem J. 1994 Oct 15;303 ( Pt 2):441-8.