ACTH (22-39)(Synonyms: Adrenocorticotropic Hormone (22-39))

发表于由

ACTH (22-39);(Synonyms: Adrenocorticotropic Hormone (22-39))

ACTH (22-39) 是促肾上腺皮质激素 (ACTH) 的一个片段。ACTH (22-39) 是 ACTH 的 22-39 序列。

ACTH (22-39)amp;;(Synonyms: Adrenocorticotropic Hormone (22-39))

ACTH (22-39) Chemical Structure

CAS No. : 37548-29-1

规格 价格 是否有货
1 mg ￥1400 询问价格 货期
5 mg ￥4200 询问价格 货期
10 mg ￥5900 询问价格 货期

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生物活性

ACTH (22-39) is an adrenocorticotropic hormone (ACTH) fragment. ACTH (22-39) is the 22-39 sequence of ACTH.

体外研究
(In Vitro)

ACTH (22-39) contains two proline residues at positions 3 and 15 from the N-terminus[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1985.06

Formula

C90H125N19O32
CAS 号

37548-29-1
Sequence

Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe
Sequence Shortening

VYPNGAEDESAEAFPLEF
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. McMillen CL, et al. Negative Ion In-Source Decay Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry for Sequencing Acidic Peptides. J Am Soc Mass Spectrom. 2016 May;27(5):847-55.