PUMA BH3

PUMA BH3;

PUMA BH3 是一种 p53 正向凋亡调控因子 (PUMA) BH3结构域多肽,作为 Bak 的直接激活剂,Kd 值为 26 nM。

PUMA BH3amp;;

PUMA BH3 Chemical Structure

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1 mg ¥1500 询问价格 货期
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生物活性

PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.

IC50 Target[1]

Bak

26 nM (Kd)

体外研究
(In Vitro)

PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM. PUMA BH3 binds Bak in the canonical BH3-binding groove, and activates Bak[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

3049.30

Formula

C128H202N42O43S

Sequence Shortening

EEQWAREIGAQLRRMADDLNAQYER

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Dai H, et al. Evaluation of the BH3-only protein Puma as a direct Bak activator. J Biol Chem. 2014 Jan 3;289(1):89-99.