Pressinoic Acid;
Pressinoic Acid是一种具有强效促肾上腺皮质激素释放活性的合成六肽。 Pressinoic Acid也是催产素 (oxytocin) 抑制剂; 它诱发母性行为。
Pressinoic Acid Chemical Structure
CAS No. : 35748-51-7
规格 | 价格 | 是否有货 | |
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1 mg | ¥800 | 询问价格 货期 | |
5 mg | ¥2800 | 询问价格 货期 | |
10 mg | ¥4800 | 询问价格 货期 |
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生物活性 |
Pressinoic Acid is a synthetic hexapeptide with potent corticotrophin-releasing activity. Pressinoic Acid is also an oxytocin inhibitor; it induces maternal behavior. |
IC50 Target |
Oxytocin[1] |
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体外研究 (In Vitro) |
Pressinoic acid, a synthetic hexapeptide that corresponds to the ring of vasopressin, exhibits corticotrophin-releasing activity in vitro in doses of 3 and 30 ng/mL[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
774.86 |
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Formula |
C33H42N8O10S2 |
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CAS 号 |
35748-51-7 |
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Sequence |
Cys-Tyr-Phe-Gln-Asn-Cys (Disulfide bridge: Cys1-Cys6) |
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Sequence Shortening |
CYFQNC (Disulfide bridge: Cys1-Cys6) |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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Solvent Solubility |
In Vitro:;
H2O Peptide Solubility and Storage Guidelines: 1.;;Calculate the length of the peptide. 2.;;Calculate the overall charge of the entire peptide according to the following table:
3.;;Recommended solution:
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参考文献 |
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Cell Assay [1] |
Single halved pituitary glands of female CFE rats weighing 100 to 150 g are preincubated for two hours in Krebs-Ringer-bicarbonate-glucose (2%) medium under 5% CO2 in O2, and then for one hour periods each with 300 ng. lysine vasopressin and the sample of vasopressin ring peptide Pressinoic Acid. The incubations are separated by a one hour ish period. The media from the pituitary incubations are added to rat adrenal quarters superfused for estimation of the steroidogenic response to the corticotrophin released. The steroidogenie effect of the unstimulated release of corticotrophin by the pituitary tissue and the possible steroidogenic effect of the peptide directly on the adrenal tissue are measured together by adding the peptide to the media from pituitary tissue incubated without peptide for one hour[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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参考文献 |
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