JMV 449;
JMV 449 是一种有效的神经降压素受体 (neurotensin receptor) 激动剂。JMV 449 显示抑制 [125I]-neurotensin 与新生小鼠脑结合的 IC50 为 0.15 nM,对收缩豚鼠回肠的 EC50 为 1.9 nM。JMV 449 对小鼠具有高效、持久的降温和缓解疼痛作用。
JMV 449 Chemical Structure
CAS No. : 139026-66-7
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100 mg | ; | 询价 | ; |
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JMV 449 的其他形式现货产品:
生物活性 |
JMV 449 is a potent neurotensin receptor agonist. JMV 449 shows an IC50 of 0.15 nM for inhibition of [125I]-neurotensin binding to neonatal mouse brain and an EC50 of 1.9 nM in contracting the guinea-pig ileum. JMV 449 has highly potent and long-lasting hypothermic and analgesic effects in the mouse[1][2]. |
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体内研究 (In Vivo) |
JMV 449 (120 pmol/mouse; i.c.v) shows analgesic effect[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
746.98 |
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Formula |
C38H66N8O7 |
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CAS 号 |
139026-66-7 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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