CTAP

CTAP;

CTAP 是一种强效、高选择性的脑渗透类阿片受体 (μ opioid receptor)拮抗剂 (IC50=3.5 nM),对 δ opioid受体 (IC50=4500 nM) 和生长抑素受体具有超过 1200 倍的选择性。CTAP 可用于 L -多巴胺 (HY-N0304) 诱导的运动障碍 (LID) 的研究。

CTAPamp;;

CTAP Chemical Structure

CAS No. : 103429-32-9

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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CTAP 的其他形式现货产品:

CTAP TFA

生物活性

CTAP is a potent, highly selective, and brain penetrant μ opioid receptor antagonist (IC50=3.5 nM) and displays over 1200-fold selectivity over δ opioid (IC50=4500 nM) and somatostatin receptors. CTAP can be used for the study of L-DOPA-induced dyskinesia (LID)[1].

IC50 Target

IC50: 3.5 nM (μ opioid receptor)
IC50: 4500 nM (δ opioid receptor)[1]

分子量

1104.30

Formula

C51H69N13O11S2

CAS 号

103429-32-9

Sequence

{d-Phe}-Cys-Tyr-{d-Trp}-Arg-Thr-{Pen}-Thr-NH2 (Disulfide bridge:Cys2-Pen7)

Sequence Shortening

{d-Phe}-CY-{d-Trp}-RT-{Pen}-T-NH2 (Disulfide bridge:Cys2-Pen7)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Mitchell J Bartlett, et al. Highly-selective µ-opioid Receptor Antagonism Does Not Block L-DOPA-induced Dyskinesia in a Rodent Model.BMC Res Notes