CEF27, Epstein-Barr Virus BRLF-1 lytic (148-156)

发表于由

CEF27, Epstein-Barr Virus BRLF-1 lytic (148-156);

CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 对应于 BRLF1 蛋白的 148-156 位氨基酸。BRLF1 是一种转录激活因子，其直接结合一些 Epstein-Barr 病毒 (EBV) 裂解基因启动子中的 GC 富集序列。

CEF27, Epstein-Barr Virus BRLF-1 lytic (148-156)amp;;

CEF27, Epstein-Barr Virus BRLF-1 lytic (148-156) Chemical Structure

CAS No. : 254110-79-7

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生物活性

CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 corresponding to amino acids 148-156 of the BRLF1 protein. BRLF1 is a transcriptional activator that binds directly to a GC-rich motif present in some Epstein-Barr virus (EBV) lytic gene promoters[1].

体外研究
(In Vitro)

Expression of the EBV immediate-early (IE) protein BRLF1 induces the lytic form of viral replication in most EBV-positive cell lines[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

302.93

Formula

HTKSVY2
CAS 号

254110-79-7
Sequence Shortening

RVRAYTYSK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Darr CD, et al. Epstein-Barr virus immediate-early protein BRLF1 induces the lytic form of viral replication through a mechanism involving phosphatidylinositol-3 kinase activation. J Virol. 2001 Jul;75(13):6135-42.