pBD-1;
pBD-1 是一种来源于猪组织的内源性组成型表达的抗菌肽 (AMP)，尤其在猪黏膜上皮部位表达。pBD-1 具有抗菌作用，并且有助于猪黏膜和系统宿主防御。
pBD-1 Chemical Structure
CAS No. : 206367-33-1
| 规格 | 是否有货 | ||
|---|---|---|---|
| 100 mg | ; | 询价 | ; |
| 250 mg | ; | 询价 | ; |
| 500 mg | ; | 询价 | ; |
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| 生物活性 |
pBD-1 is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites. pBD-1 has antimicrobial activities and contributes to mucosal and systemic host defenses in pigs[1]. |
IC50 Target |
IC50: bacterial[1] |
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| 体外研究 (In Vitro) |
In a northern blot analysis, pBD-1 mRNA only expresses in ongue epithelial tissues from 4-5 week old pigs[1].In RT-PCR analysis, pBD-1 message throughout the epithelia of the respiratory (from nasal septum to lung) and gastrointestinal (from esophagus to rectum) tracts. In addition, it is detected in thymus, spleen, lymph node, brain, liver, kidney, urinary bladder, testis, skin, heart, muscle, bone marrow, alveolar macrophages, peripheral blood neutrophils and the umbilical cord. The only cells evaluated that does not express pBD-1 are peripheral blood mononuclear cells[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
7065.98 |
| Formula |
C310H543N91O73S11 |
| CAS 号 |
206367-33-1 |
| Sequence |
Met-Arg-Leu-His-Arg-Leu-Leu-Leu-Val-Phe-Leu-Leu-Met-Val-Leu-Leu-Pro-Val-Pro-Gly-Leu-Leu-Lys-Asn-Ile-Gly-Asn-Ser-Val-Ser-Cys-Leu-Arg-Asn-Lys-Gly-Val-Cys-Met-Pro-Gly-Lys-Cys-Ala-Pro-Lys-Met-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Met-Pro-Gln-Val-Lys-Cys-Cys-Lys-Arg-Lys |
| Sequence Shortening |
MRLHRLLLVFLLMVLLPVPGLLKNIGNSVSCLRNKGVCMPGKCAPKMKQIGTCGMPQVKCCKRK |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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