POT-4 TFA(Synonyms: AL-78898A TFA)

发表于由

POT-4 TFA;(Synonyms: AL-78898A TFA)

POT-4 TFA (AL-78898A TFA)，一种 Compstatin 衍生物，是补体因子 C3 激活的有效抑制剂。POT-4 TFA 可用于与年龄相关的黄斑变性的研究。

POT-4 TFAamp;;(Synonyms: AL-78898A TFA)

POT-4 TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
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POT-4 TFA 的其他形式现货产品:

POT-4

生物活性

POT-4 TFA (AL-78898A TFA), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 TFA can be used for age-related macular degeneration research[1][2].

体外研究
(In Vitro)

A derivative of compstatin, a potent C3 inhibitor, POT-4 is a cyclic peptide that exhibits binding activity to C3, preventing cleavage to its active fragments C3a and C3b[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial

分子量

1741.87

Formula

C74H103F3N22O20S2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. S. Kaushal, et al. Complement C3 inhibitor POT-4: Clinical Safety of Intravitreal Administration. ARVO Annual Meeting Abstract, 2009 Apr.

    [2]. Robyn Troutbeck, et al. Therapeutic targeting of the complement system in age-related macular degeneration: a review. Clin Exp Ophthalmol. Jan-Feb 2012;40(1):18-26.