H-D-Phe-Pip-Arg-pNA(Synonyms: S-2238)

发表于由

H-D-Phe-Pip-Arg-pNA;(Synonyms: S-2238)

H-D-Phe-Pip-Arg-pNA (S-2238) 是一种显色底物，在凝血酶的天然底物纤维蛋白原 α 链的 N 端部分之后形成。H-D-Phe-Pip-Arg-pNA 对凝血酶有特异性，用于测定抗凝血酶肝素辅因子 (AT-III)。使用 H-D-Phe-Pip-Arg-pNA 进行的 AT-III 分析灵敏、准确、易于执行。

H-D-Phe-Pip-Arg-pNAamp;;(Synonyms: S-2238)

H-D-Phe-Pip-Arg-pNA Chemical Structure

CAS No. : 64815-81-2

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H-D-Phe-Pip-Arg-pNA 的其他形式现货产品:

H-D-Phe-Pip-Arg-pNA acetate

生物活性

H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform[1][2].

分子量

552.63

Formula

C27H36N8O5
CAS 号

64815-81-2
Sequence Shortening

{D-Phe}-{Pip}-R-pNA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Goodnight SH Jr, et al. Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. Am J Clin Pathol. 1980;73(5):639-647.

    [2]. Voorthuizen H, Kluft C. Improved assay conditions for automated antithrombin III determinations with the chromogenic substrate S-2238. Thromb Haemost. 1984;52(3):350-353.