[Leu31,Pro34]-Neuropeptide Y(human,rat);
[Leu31,Pro34]-Neuropeptide Y(human,rat) 是一种特定的神经肽 Y Y1 受体激动剂。[Leu31,Pro34]-Neuropeptide Y(human,rat) 也激活 Y4,Y5。[Leu31,Pro34]-Neuropeptide Y(human,rat) 可以增加麻醉大鼠的血压,也增加饮食摄入量。
[Leu31,Pro34]-Neuropeptide Y(human,rat) Chemical Structure
CAS No. : 132699-73-1
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100 mg | ; | 询价 | ; |
250 mg | ; | 询价 | ; |
500 mg | ; | 询价 | ; |
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[Leu31,Pro34]-Neuropeptide Y(human,rat) 的其他形式现货产品:
生物活性 |
[Leu31,Pro34]-Neuropeptide Y(human,rat) is a specific neuropeptide Y Y1 receptor agonist. [Leu31,Pro34]-Neuropeptide Y(human,rat) slao activates Y4, Y5. [Leu31,Pro34]-Neuropeptide Y(human,rat) can increase blood pressure in anesthetized rats and increases food intake[1][2]. |
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IC50 Target[1][2] |
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体外研究 (In Vitro) |
[Leu31,Pro34]-Neuropeptide Y(human,rat) has Ki values of 0.39 nM, 0.499 nM, 0.31 nM for Y1, Y4, Y5 in HEK cell lines. [Leu31,Pro34]-Neuropeptide Y(human,rat) has a Ki of >1000 for Y2 in HEK cell lines[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
[Leu31,Pro34]-Neuropeptide Y(human,rat) (30 pmol; microinjected into paraventricular nucleus) increases food intake in the rats (350±400 g)[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
4240.73 |
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Formula |
C189H284N54O56S |
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CAS 号 |
132699-73-1 |
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Sequence |
Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2 |
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Sequence Shortening |
YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY-NH2 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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Solvent Solubility |
In Vitro:;
H2O Peptide Solubility and Storage Guidelines: 1.;;Calculate the length of the peptide. 2.;;Calculate the overall charge of the entire peptide according to the following table:
3.;;Recommended solution:
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参考文献 |
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