H3K4(Me3) (1-20)

H3K4(Me3) (1-20);

H3K4(Me3) (1-20),一种组蛋白多肽,组蛋白 H3 对赖氨酸 4 (H3K4 me3) 的三甲基化在活性的常染色质中发现。

H3K4(Me3) (1-20)amp;;

H3K4(Me3) (1-20) Chemical Structure

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生物活性

H3K4(Me3) (1-20) is a histone peptide. Trimethylation of histone H3 on lysine 4 (H3K4 me3) is found in active euchromatin but not in silent heterochromatin[1][2].

分子量

2226.64

Formula

C94H174N35O27

Sequence

Ala-Arg-Thr-{Lys(Me3)}-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu

Sequence Shortening

ART-{Lys(Me3)}-QTARKSTGGKAPRKQL

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Mulder KW, et al. Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complex. Nucleic Acids Res. 2007;35(7):2428-2439.

    [2]. Fujino T, et al. Alteration of histone H3K4 methylation in glomerular podocytes associated with proteinuria in patients with membranous nephropathy. BMC Nephrol. 2016;17(1):179. Published 2016 Nov 17.