[Asp371]-Tyrosinase (369-377), human

[Asp371]-Tyrosinase (369-377), human;

Tyrosinase 369-377, human 是一种来自酪氨酸酶 (tyrosinase) 的 HLA-A2.1 限制性表位多肽,已被应用于开发具有混合疗效的肿瘤靶向疫苗。

[Asp371]-Tyrosinase (369-377), humanamp;;

[Asp371]-Tyrosinase (369-377), human Chemical Structure

CAS No. : 168650-46-2

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生物活性

Tyrosinase 369-377, human is a HLA-A2.1-restricted epitope derived from tyrosinase, has been used to develop tumor-targeted vaccines with mixed efficacy[1][2].

分子量

1031.16

Formula

C42H66N10O16S2

CAS 号

168650-46-2

Sequence

Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val

Sequence Shortening

YMDGTMSQV

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Guillaume B, et al. Analysis of the processing of seven human tumor antigens by intermediate proteasomes. J Immunol. 2012 Oct 1;189(7):3538-47.

    [2]. Mitchell MS, et al. Phase I trial of adoptive immunotherapy with cytolytic T lymphocytes immunized against a tyrosinase epitope. J Clin Oncol. 2002 Feb 15;20(4):1075-86.

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