Peptide 78

Peptide 78; 纯度: 98.13%

Peptide 78,一种趋化细胞因子,由 78 个氨基酸组成,是 IL-8 或 C-X-C 趋化因子超基因家族的蛋白成员。Peptide 78 诱导中性粒细胞 (PMN) 在类风湿性关节炎 (RA) 关节方面发挥重要作用。

Peptide 78amp;;

Peptide 78 Chemical Structure

CAS No. : 132116-62-2

规格 价格 是否有货 数量
5 mg ¥2000 In-stock
10 mg ¥3500 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

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Peptide 78 相关产品


  • Bioactive Compound Library Plus
  • Peptide Library


Peptide 78, a chemotactic cytokine, a 78 amino acid protein member of the IL-8 or C-X-C chemokine supergene family. ENA-78 plays an important role in the elicitation of predominantly neutrophils (PMNs) into the joints of rheumatoid arthritis (RA)[1].

(In Vitro)

Peptide 78, a potent PMN chemotaxin, in the conditioned medium of human pulmonary epithelial cells (A549) stimulated with TNF-α (20 ng/mL) or IL-1β (10 ng/mL). Peptide 78 is an 8.3-kD protein with 78 amino acids containing 4 cysteines positioned identically to those of IL-8 and its homologues. Peptide 78 belongs to a supergene family that includes platelet factor-4, platelet basic protein, and its cleavage products (connective tissue activating peptide-III, β-thromboglobulin, and interferon-γ-inducible protein, macrophage inflammatory protein-2α, and macrophage inflammatory protein-2β)[1].
Peptide 78 shares several properties of PMN activation similar to either NAP-2 or LL-8. Peptide 78 stimulation of PMNs results in significant chemotactic activity, release of elastase from cytochalasin-B-pretreated cells, and the induction of free, cytosolic calcium release. Peptide 78 aids in the recruitment of PMNs into inflamed joints of RA. Peptide 78 represents one of the most abundant chemokines present in RA synovial fluid.Peptide 78 in rheumatoid arthritis synovial fluids is biologically active. Peptide 78 appears to account for almost half of the RA synovial fluid PMN chemotactic activity in vitro[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.







Sequence Shortening



Room temperature in continental US; may vary elsewhere.


Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

In Vitro:;

H2O : 100 mg/mL (64.82 mM; Need ultrasonic)

浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.6482 mL 3.2410 mL 6.4821 mL
5 mM 0.1296 mL 0.6482 mL 1.2964 mL
10 mM 0.0648 mL 0.3241 mL 0.6482 mL


储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

  • [1]. A E Koch, et al. Epithelial neutrophil activating peptide-78: a novel chemotactic cytokine for neutrophils in arthritis. J Clin Invest. 1994 Sep;94(3):1012-8.