OM99-2 TFA，一种八残基拟肽，人脑 memapsin 2 的紧密结合抑制剂，其 Ki 值为 9.58 nM。OM99-2 TFA 显著促进了 BACE1 抑制剂的开发，具有研究阿尔茨海默症的潜力。
OM99-2 TFA Chemical Structure
CAS No. : 2504147-81-1
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OM99-2 TFA, an eight residue peptidomimetic, tight-binding inhibitor of human brain memapsin 2 with a Ki value of 9.58 nM. OM99-2 TFA is significantly advanced the development of BACE1 inhibitor. OM99-2 has the potential for the research of the Alzheimer’s disease.
Ki: 9.58 nM (memapsin 2)
Memapsin 2 (BACE) is an aspartyl protease known as beta-secretase that acts on the production of the beta-amyloid peptide in the human brain.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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