Xenin-8 TFA 是 Xenin 的 C 端八肽，也是 Xenin 的生物活性片段。Xenin 属于神经降压素/xenopsin 家族的多肽。Xenin-8 TFA 刺激基础胰岛素分泌，并以剂量依赖的方式增强胰岛素对葡萄糖的反应 (EC50=0.16 nM)。
Xenin-8 TFA Chemical Structure
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Xenin-8 TFA, a C-terminal octapeptide, is a biologically active fragment of Xenin. Xenin is a 25-amino acid peptide of the neurotensin/xenopsin family. Xenin-8 TFA stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner (EC50=0.16 nM).
Xenin-8 TFA augments Arginine-induced insulin release (by 40%) and potentiates the glucagon responses to both Arginine (by 60%), Carbachol (by 50%). Xenin-8 TFA counteracts the inhibition of glucagon release induced by increasing the glucose concentration.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Room temperature in continental US; may vary elsewhere.
Please store the product under the recommended conditions in the Certificate of Analysis.
Peptide Solubility and Storage Guidelines:
1.;;Calculate the length of the peptide.
2.;;Calculate the overall charge of the entire peptide according to the following table: