Caloxin 2A1

发表于2023年11月3日由Whatman官网

Caloxin 2A1;

Caloxin 2A1 是一种细胞外质膜 Ca²⁺-ATPase (PMCA) 肽抑制剂。Caloxin 2A1 不影响基础 Mg²⁺-ATPase 或 Na⁺-K⁺-ATPase。

Caloxin 2A1amp;;

Caloxin 2A1 Chemical Structure

CAS No. : 350670-85-8

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

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Caloxin 2A1 的其他形式现货产品:

Caloxin 2A1 TFA

生物活性	Caloxin 2A1 is an extracellular plasma membrane Ca²⁺-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg²⁺-ATPase or Na⁺-K⁺-ATPase^[1].
体外研究 (In Vitro)	Caloxin 2A1 inhibits Ca²⁺-Mg²⁺-ATPase in human erythrocyte leaky ghosts, but it does not affect basal Mg²⁺-ATPase or Na⁺-K⁺-ATPase in the ghosts or Ca²⁺-Mg²⁺-ATPase in the skeletal muscle sarcoplasmic reticulum. Caloxin 2A1 also inhibits Ca²⁺-dependent formation of the 140-kDa acid-stable acylphosphate^[1]. Caloxin 2A1 increases airway smooth muscle cells (ASMCs) apoptosis^[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	1478.52
Formula	C₆₄H₉₁N₁₉O₂₂
CAS 号	350670-85-8
Sequence Shortening	VSNSNWPSFPSSGGG-NH2
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. J Chaudhary, et al. Caloxin: a novel plasma membrane Ca2+ pump inhibitor. Am J Physiol Cell Physiol. 2001 Apr;280(4):C1027-30. [2]. Yi-fei Chen, et al. Plasma membrane Ca2+-ATPase regulates Ca2+ signaling and the proliferation of airway smooth muscle cells. Eur J Pharmacol. 2014 Oct 5;740:733-41.