Argifin;
Argifin 是一种由土壤微生物产生的次纳摩尔级别的几丁质酶 (chitinase) 抑制剂，对粘质沙雷菌几丁质酶 A 和 B、烟曲霉几丁质酶 B1 和人壳三糖酶作用的 IC50 值分别为 0.025 μM、6.4 μM、1.1 μM 和 4.5 μM。
Argifin Chemical Structure
CAS No. : 243975-37-3
| 规格 | 是否有货 | ||
|---|---|---|---|
| 5 mg | 询价 | ||
| 10 mg | 询价 | ||
| 25 mg | 询价 |
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| 生物活性 |
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively[1]. |
IC50 Target |
IC50: 0.025 μM (SmChiA), 6.4 μM (SmChiB), 1.1 μM (Aspergillus fumigatus chitinase B1), 4.5 μM (human chitotriosidase)[1] |
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| 体外研究 (In Vitro) |
Argifin inhibits L. cuprina chitinase with IC50 values of 3.7 μM at 37 ºC and 0.10 μM at 20 ºC[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| 体内研究 (In Vivo) |
Argifin has the ability to inhibit L. cuprina molting[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
675.69 |
| Formula |
C29H41N9O10 |
| CAS 号 |
243975-37-3 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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