Myelin Basic Protein(87-99) TFA

发表于由

Myelin Basic Protein(87-99) TFA;

Myelin Basic Protein(87-99) TFA 是一种致脑肽，可诱导碱性蛋白特异性 T 细胞增殖。Myelin Basic Protein(87-99) TFA 在外周血单核细胞中引起 Th1 极化，与多发性硬化症 (MS) 有关。

Myelin Basic Protein(87-99) TFAamp;;

Myelin Basic Protein(87-99) TFA Chemical Structure

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生物活性

Myelin Basic Protein(87-99) TFA is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein(87-99) TFA causes a Th1 polarization in peripheral blood mononuclear cells with is implicated of multiple sclerosis (MS)[1][2].

分子量

1669.82

Formula

C76H115N20O19F3
Sequence

Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro
Sequence Shortening

VHFFKNIVTPRTP
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. R E Jones, et al. The synthetic 87-99 peptide of myelin basic protein is encephalitogenic in Buffalo rats. J Neuroimmunol. 1992 Apr;37(3):203-12.

    [2]. George Deraos, et al. Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease. J Med Chem. 2008 Dec 25;51(24):7834-42.