1-Alaninechlamydocin

发表于由

1-Alaninechlamydocin;

1-Alaninechlamydocin 是一种环状四肽，是一种有效的 HDAC 抑制剂 (IC50=6.4 nM)。 1-Alaninechlamydocin 在 MIA PaCa-2 细胞中诱导 G2/M 细胞周期停滞和凋亡 (apoptosis)。

1-Alaninechlamydocinamp;;

1-Alaninechlamydocin Chemical Structure

CAS No. : 141446-96-0

规格 是否有货
100 mg ; 询价 ;
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生物活性

1-Alaninechlamydocin, a cyclic tetrapeptide, is a potent HDAC inhibitor (IC50=6.4 nM). 1-Alaninechlamydocin induces G2/M cell cycle arrest and apoptosis in MIA PaCa-2 cells[1].

IC50 Target[1]

HDAC

6.4 nM (IC50)

分子量

512.60

Formula

C27H36N4O6
CAS 号

141446-96-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Du L, et al. A potent HDAC inhibitor, 1-alaninechlamydocin, from a Tolypocladium sp. induces G2/M cell cycle arrest and apoptosis in MIA PaCa-2 cells. J Nat Prod. 2014;77(7):1753-1757.