3-Carene is a bicyclic monoterpene in essential oils extracted from pine trees. 3-Carene inhibits nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression, and with antinociceptive effect. 3-Carene stimulates the activity and expression of alkaline phosphatase that is an early phase marker of osteoblastic differentiation[1][2].
分子量
136.23
Formula
C10H16
CAS 号
13466-78-9
中文名称
3-蒈烯
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Huang XL, e tal. Anti-inflammatory and antinociceptive effects of active ingredients in the essential oils from Gynura procumbens, a traditional medicine and a new and popular food material.J Ethnopharmacol. 2019 Jul 15;239:111916.
[2]. Jeong JG, et al. Low concentration of 3-carene stimulates the differentiation of mouse osteoblastic MC3T3-E1 subclone 4 cells. Phytother Res. 2008 Jan;22(1):18-22.
上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Makisterone A
Makisterone A 是一种 28 碳的蜕皮激素,为蜜蜂 Apis mellifera 中主要的游离蛹蜕皮激素。
Makisterone A Chemical Structure
CAS No. : 20137-14-8
规格
是否有货
100 mg
询价
250 mg
询价
500 mg
询价
* Please select Quantity before adding items.
生物活性
Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera[1].
分子量
494.66
Formula
C28H46O7
CAS 号
20137-14-8
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. M.F.Feldlaufer, et al. Makisterone A: The major ecdysteroid from the pupa of the honey bee, Apis mellifera. Insect Biochemistry. 1985, 15 (5):597-600.
上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Lucidenic acid C(Synonyms: 赤芝酸 C)
Lucidenic acid C 是从灵芝中分离得到的天然产物,可抑制 PMA 诱导的 MMP-9 活性,对肝癌细胞具有抗侵袭作用。
Lucidenic acid C Chemical Structure
CAS No. : 95311-96-9
规格
价格
是否有货
1 mg
¥2860
询问价格 & 货期
5 mg
¥8570
询问价格 & 货期
* Please select Quantity before adding items.
生物活性
Lucidenic acid C is a natural compound isolated from Ganoderma lucidum, inhibits PMA-induced MMP-9 activity, with anti-invasive effect on hepatoma cells[1].
IC50 & Target
MMP-9[1]
分子量
476.60
Formula
C27H40O7
CAS 号
95311-96-9
中文名称
赤芝酸 C
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Weng CJ, et al. The anti-invasive effect of lucidenic acids isolated from a new Ganoderma lucidum strain. Mol Nutr Food Res. 2007 Dec;51(12):1472-7.
Cyperotundone is a sesquiterpene isolated from Nagarmotha (Cyperus rotundus)[1][2].
分子量
218.33
Formula
C15H22O
CAS 号
3466-15-7
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Hashmat Imam, et al. The incredible benefits of Nagarmotha (Cyperus rotundus). 2014, 4(1): 23-27.
[2]. Yong JooPark, et al. Sesquiterpenes from Cyperus rotundus and 4α,5α-oxidoeudesm-11-en-3-one as a potential selective estrogen receptor modulator. Biomedicine & Pharmacotherapy. Volume 109, January 2019, Pages 1313-1318.
上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Anti-inflammatory agent 5
Anti-inflammatory agent 5 显示出对 LPS 诱导的 BV-2 小胶质细胞产生 NO 的有效抑制作用。
Anti-inflammatory agent 5 Chemical Structure
规格
是否有货
5 mg
询价
10 mg
询价
25 mg
询价
* Please select Quantity before adding items.
生物活性
Anti-inflammatory agent 5 displays potent inhibition of NO generation in lipopolysaccharide-induced BV-2 microglial cells.
分子量
264.32
Formula
C15H20O4
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Li-Bin L, et al. Eremophilane Sesquiterpenoids with Antibacterial and Anti-inflammatory Activities from the Endophytic Fungus Septoria rudbeckiae. J Agric Food Chem. 2021 Oct 13;69(40):11878-11889.
Epibetulinic acid exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].
IC50 & Target[1]
PGE2
0.6 μM (IC50)
NO
0.7 μM (IC50)
分子量
456.70
Formula
C30H48O3
CAS 号
38736-77-5
中文名称
表白桦脂酸
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14(5):1573-9.
Euscaphic acid, a DNA polymerase inhibitor, is a triterpene from the root of the R. alceaefolius Poir. Euscaphic inhibits calf DNA polymerase α (pol α) and rat DNA polymerase β (pol β) with IC50 values of 61 and 108 μM[1]. Euscaphic acid induces apoptosis[2].
IC50 & Target
IC50: 61 μM (calf DNA polymerase α); 108 μM (rat DNA polymerase β)[1]; apoptosis[2]
体外研究 (In Vitro)
Euscaphic acid induces apoptosis and cell cycle arrest in NPC cells by suppression of the PI3K/AKT/mTOR signaling pathway[2].
Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
488.70
Formula
C30H48O5
CAS 号
53155-25-2
中文名称
野鸦椿酸
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶解性数据
In Vitro:
DMSO : 250 mg/mL (511.56 mM; Need ultrasonic)
配制储备液
浓度溶剂体积质量
1 mg
5 mg
10 mg
1 mM
2.0462 mL
10.2312 mL
20.4625 mL
5 mM
0.4092 mL
2.0462 mL
4.0925 mL
10 mM
0.2046 mL
1.0231 mL
2.0462 mL
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:
[1]. Murakami C, et al. Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases. Biochim Biophys Acta. 2002 Apr 29;1596(2):193-200.
[2]. Dai W, et al. Euscaphic acid inhibits proliferation and promotes apoptosis of nasopharyngeal carcinoma cells by silencing the PI3K/AKT/mTOR signaling pathway. Am J Transl Res. 2019 Apr 15;11(4):2090-2098.