ReverScript3 逆转录酶Ⅲ 品牌:FUJIFILM Wako


ReverScript3

逆转录酶Ⅲ

品牌:FUJIFILM Wako
CAS No.:
储存条件:-20℃
纯度:
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

293-59401

for Genetic Research 10 tests

ReverScript3                                                      逆转录酶Ⅲ             品牌:FUJIFILM Wako


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Thioredoxin 2 Yeast (rec.) 硫氧还蛋白2酵母(rec.) 品牌:AbFrontier


Thioredoxin 2 Yeast (rec.)

硫氧还蛋白2酵母(rec.)

品牌:AbFrontier
CAS No.:
储存条件:-80℃
纯度:
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

YIF-LF-P0052

0.5 mg

Thioredoxin 2 Yeast (rec.)                                                      硫氧还蛋白2酵母(rec.)            品牌:AbFrontier


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β-Amyloid (1-16)(Synonyms: Amyloid β-Protein (1-16))

β-Amyloid (1-16);(Synonyms: Amyloid β-Protein (1-16))

β-Amyloid (1-16) 是可参与金属结合的β-淀粉样蛋白片段。 β-淀粉样蛋白是在阿尔茨海默病患者的脑中形成淀粉样斑块的肽。

β-Amyloid (1-16)amp;;(Synonyms: Amyloid β-Protein (1-16))

β-Amyloid (1-16) Chemical Structure

CAS No. : 131580-10-4

规格 价格 是否有货 数量
1 mg ¥1100 In-stock
5 mg ¥3900 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

beta;-Amyloid (1-16) 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Neuronal Signaling Compound Library
  • Anti-Alzheimer’s Disease Compound Library
  • Neurodegenerative Disease-related Compound Library
  • Peptide Library

生物活性

β-Amyloid (1-16) is a β-Amyloid protein fragment involved in metal binding. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer’s disease (AD) patients.

IC50 Target

Amyloid-β[1]

体内研究
(In Vivo)

β-amyloid (1-16) fragment is considered as valid models to examine the contribution of the key histidine residues (His , His in mouse and His , His , His in human fragments) to the Ab–Cu2+ interaction. Oxidation targets for β-Amyloid (1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aβ in senile plaque of Alzheimer’s disease with β-Amyloid (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of -Amyloid and free radical damage[1]. β-amyloid (1-16) is the minimal amino acidic sequence display a Cu coordination mode which involves three Histidines (His6, His13 and His14). β-amyloid (1-16) is supposed to be involved in metal binding[2]. Human β-amyloid interacts with zinc ions through its metal-binding domain 1-16. The C-tails of the two polypeptide chains of the rat Aβ(1-16) dimer are oriented in opposite directions to each other, which hinders the assembly of rat Aβ dimers into oligomeric aggregates. Thus, the differences in the structure of zinc-binding sites of human and rat β-Amyloid (1-16), their ability to form regular cross-monomer bonds, and the orientation of their hydrophobic C-tails could be responsible for the resistance of rats to Alzheimer’s disease[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1955.04

Formula

C84H119N27O28

CAS 号

131580-10-4

Sequence

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys

Sequence Shortening

DAEFRHDSGYEVHHQK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Kowalik-Jankowska T, et al. Coordination abilities of the 1-16 and 1-28 fragments of beta-amyloid peptide towards copper(II) ions: a combined potentiometric and spectroscopic study. J Inorg Biochem. 2003 Jul 1;95(4):270-82.

    [2]. Minicozzi V, et al. Identifying the minimal copper- and zinc-binding site sequence in amyloid-beta peptides. J Biol Chem. 2008 Apr 18;283(16):10784-92.

    [3]. Istrate AN, et al. NMR solution structure of rat aβ(1-16): toward understanding the mechanism of rats’ resistance to Alzheimer’s disease. Biophys J. 2012 Jan 4;102(1):136-43.

1.10020.0001-Merck硝酸盐测试纸

  • 型号 1.10020.0001
  • 品牌 Merck Millipore密理博
  • 【简单介绍】
    品牌 其他品牌

    Merck硝酸盐测试纸,包装小巧,所用试剂均装配在测试盒内,便于携带,高质量的化学试剂,保证您的测试结果准确可靠.

    产品名称:硝酸盐检测试纸

    品牌信息:Merck

    测量范围:10 – 25 – 50 – 100 – 250 – 500 mg/l NO3¯(货号:1.10020.0001)

    规格包装:100条/盒

    产品货号:1.10020.0001

    产品特点:

    简单而高精度的试纸条,能完成溶液中30多种参数的测试

    测试过程简单明了,结果易于读取就像pH测试条一样

    包装小巧,所用试剂均装配在测试盒内,便于携带

    高质量的化学试剂,保证您的测试结果准确可靠.

    使用方法:

    1取出一根测试条并迅速盖上密封盖;

    2沾取被测试样一秒钟取出轻甩干;

    3等待一分钟显色后与标准色卡比色读数

    Merck硝酸盐测试纸  1.10020.0001

    订货信息:

    1.10020.0001-Merck硝酸盐测试纸

     

Somatostatin-28 (1-12)(Synonyms: 1-12-Somatostatin-28)

Somatostatin-28 (1-12);(Synonyms: 1-12-Somatostatin-28)

Somatostatin-28 (1-12) 是生长抑素片段,在脑组织中监测以追踪生长抑素的加工。

Somatostatin-28 (1-12)amp;;(Synonyms: 1-12-Somatostatin-28)

Somatostatin-28 (1-12) Chemical Structure

CAS No. : 81286-16-0

规格 价格 是否有货
1 mg ¥1400 询问价格 货期
5 mg ¥5600 询问价格 货期
10 mg ¥9500 询问价格 货期

* Please select Quantity before adding items.

生物活性

Somatostatin-28 (1-12) is a somatostatin fragment that is monitored in brain tissue to track processing of somatostatin.

分子量

1244.33

Formula

C49H81N17O19S

CAS 号

81286-16-0

Sequence

Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu

Sequence Shortening

SANSNPAMAPRE

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Asp-Asp-Asp-Asp-Asp

Asp-Asp-Asp-Asp-Asp;

Asp-Asp-Asp-Asp-Asp 是由 5 个天冬氨酸残基组成的多肽。

Asp-Asp-Asp-Asp-Aspamp;;

Asp-Asp-Asp-Asp-Asp Chemical Structure

CAS No. : 124219-00-7

规格 价格 是否有货
1 mg ¥500 询问价格 货期
5 mg ¥1000 询问价格 货期
10 mg ¥1400 询问价格 货期

* Please select Quantity before adding items.

生物活性

Asp-Asp-Asp-Asp-Asp is a peptide consists of 5 Asp.

分子量

593.45

Formula

C20H27N5O16

CAS 号

124219-00-7

Sequence

Asp-Asp-Asp-Asp-Asp

Sequence Shortening

DDDDD

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Cytochrome b5, Human, recombinant, Solution 品牌:FUJIFILM Wako


Cytochrome b5, Human, recombinant, Solution

品牌:FUJIFILM Wako
CAS No.:
储存条件:-80℃
纯度:
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

035-20791

for Cellbiology 100 ug

Cytochrome b5, Human, recombinant, Solution                                                                品牌:FUJIFILM Wako


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* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动,恕不另行通知,确切详情请联系上海金畔生物科技有限公司。

KKI-5(Synonyms: 激肽释放酶抑制剂)

KKI-5;(Synonyms: 激肽释放酶抑制剂)

KKI-5 是一种特异性的组织激肽释放酶 (kallikrein) 抑制剂。KKI-5 可降低乳腺癌细胞浸润。

KKI-5amp;;(Synonyms: 激肽释放酶抑制剂)

KKI-5 Chemical Structure

CAS No. : 97145-43-2

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

KKI-5 的其他形式现货产品:

KKI-5 (TFA)

生物活性

KKI-5 is a specific inhibitor of tissue kallikrein. KKI-5 can attenuate breast cancer cell invasion[1].

IC50 Target

Kallikrein Inhibitor

体外研究
(In Vitro)

The KKI-5 Peptide corresponds to aa386-391 of bovine kininogen-1 that encompasses the aa388-389 kallikrein proteolytic site. The synthetic KKI-5 can attenuate breast cancer cell invasion, therefore it is investigated for its role in invasion and metastasis of cancer cells.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

773.88

Formula

C35H55N11O9

CAS 号

97145-43-2

Sequence

Ac-Pro-Phe-Arg-Ser-Val-Gln-NH2

Sequence Shortening

Ac-PFRSVQ-NH2

中文名称

激肽释放酶抑制剂

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Deshpande MS, et al. Mapping the binding site of tissue kallikrein: preparation and testing of all possible substrate analog inhibitors homologous with the sequence of kininogen between Ser386 and Gln392. J Med Chem. 1992 Aug 21;35(17):3094-102.

1.05559.0001-美国Millipore RP-18薄层层析板

  • 型号 1.05559.0001
  • 品牌 Merck Millipore密理博
  • 【简单介绍】
    品牌 其他品牌

    美国Millipore RP-18薄层层析板,RP-2、RP-8、RP-18板基于脂肪族烷烃改性硅胶60,氨基改性NH2硅胶板提供弱碱性离子交换作用,对带电化合物具有极高的选择性。

    美国Millipore RP-18薄层层析板  1.05559.0001

    改性硅胶TLC板提供额外的选择性,并大幅拓展薄层色谱应用范围

    它们满足要求严格的TLC的分离,同时亦可作为HPLC的先导技术

    RP-2、RP-8、RP-18板基于脂肪族烷烃改性硅胶60

    氨基改性NH2硅胶板提供弱碱性离子交换作用,对带电化合物具有极高的选择性

    CN和二醇改性硅胶板具有中等级性,适用于正相和反相系统 

    虽然硅胶层析板适合分析绝大多数的化合物,但是仍有一些化合物并不适合。对于极性极小或极大的化合物,通常要用反相板来分离。同时,反相板分离的条件还可以和HPLC关联起来,使其成为和HPLC相匹配的分离手段。

    RP改性硅胶板

    RP-2、RP-8、RP-18板由脂肪族烷烃改性硅胶60制备而成的

    链长与改性程度两方面因素,决定溶剂体系对水的耐受性,且深刻影响薄层板对分析物的保留能力

    相同溶剂体系下,分析物在RP-2、RP-8、RP-18上的保留时间依次增加

    HPTLC RP-2吸附剂对水溶液具有更高的极性和亲和性,可耐受高达80%的水

    而较长的碳链RP-8,RP-18可在含有高达60%水溶剂体系中使用

    NH2改性硅胶板

    氨基改性NH2板提供弱碱性离子交换作用,对带电化合物具有特殊选择性

    对于许多应用,可以作为PEI纤维素的替代品

    由于在改性板上分离的大多数物质是无色的,因此大多数改性硅胶板含有蓝色荧光和酸稳定的紫外线的指示剂F254S

    利用荧光猝灭法检测254nm处吸收短波紫外线的样品

    改性硅胶板的优势

    结果对大气湿度的依赖性较小

    允许使用含水溶剂体系

    PR改性硅胶HPLC/LPLC具有良好的相关性

    对于不稳定物质,无催化活性(如氧化降解)的改性硅胶TLC板提供额外的选择性,大幅拓展TLC应用范围
    美国Millipore RP-18薄层层析板  1.05559.0001

    技术参数:

    填料:Silica gel 60 RP-18 F254s

    尺寸:20x20cm

    涂层厚度:200μm

    材质:铝

    包装规格:20块/盒

     

Nociceptin (1-13), amide

Nociceptin (1-13), amide;

Nociceptin (1-13), amide 是一种有效的阿片受体 ORL1 (OP4) 受体激动剂,对小鼠输精管 pEC50 值为 7.9,与大鼠前脑膜结合的 Ki 值为 0.75 nM。

Nociceptin (1-13), amideamp;;

Nociceptin (1-13), amide Chemical Structure

CAS No. : 178064-02-3

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

Nociceptin (1-13), amide 的其他形式现货产品:

Nociceptin (1-13), amide TFA

生物活性

Nociceptin (1-13), amide is a potent ORL1 receptor (opioid receptor-like 1 receptor, OP4) agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes[1][2].

IC50 Target

Ki: 0.75 nM (binding to rat forebrain membranes)[1]
pEC50: 7.9 (in mouse vas deferens)[2]

体内研究
(In Vivo)

ORL1受体激动剂

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1381.59

Formula

C61H100N22O15

CAS 号

178064-02-3

Sequence Shortening

FGGFTGARKSARK-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Varani K, et al. Nociceptin receptor binding in mouse forebrain membranes: thermodynamic characteristics and structure activity relationships. Br J Pharmacol. 1998 Dec;125(7):1485-90.

    [2]. Calo’ G, et al. Pharmacology of nociceptin and its receptor: a novel therapeutic target. Br J Pharmacol. 2000 Apr;129(7):1261-83.