Secologanin

天然产物 糖类和糖苷 Saccharides and Glycosides

Secologanin; 纯度: ge;94.0%

Secologanin 是一种裂环烯醚萜苷类化合物,是生物活性单萜类吲哚类生物碱 (如利血平 (HY-N0480)、Ajmaline 和长春碱) 生物合成的关键萜类中间体。Secologanin 合成酶 (细胞色素 P450 亚型 CYP72A1) 催化 loganin 氧化裂解为 Secologanin。

Secologanin

Secologanin Chemical Structure

CAS No. : 19351-63-4

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Secologanin 相关产品

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生物活性

Secologanin, a secoiridoid glucoside, is a pivotal terpenoid intermediate in the biosynthesis of biologically active monoterpenoid indole alkaloids such as reserpine, ajmaline, and vinblastine. Secologanin synthase (cytochrome P450 isoform CYP72A1) catalyzes the oxidative cleavage of loganin into Secologanin[1][2].

分子量

388.37

Formula

C17H24O10

CAS 号

19351-63-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
In solvent -80deg;C 6 months
-20deg;C 1 month
参考文献
  • [1]. Inoue K. Yakugaku Zasshi. 2005;125(1):31-49. doi:10.1248/yakushi.125.31

    [2]. Irmler S, et al. Indole alkaloid biosynthesis in Catharanthus roseus: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase. Plant J. 2000;24(6):797-804.

Mudanpioside C

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Mudanpioside C 

Mudanpioside C 是一种多萜类化合物,源于芍药类植物。

Mudanpioside C

Mudanpioside C Chemical Structure

CAS No. : 172760-03-1

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生物活性

Mudanpioside C is a monoteepenoid isolated from Paeonia lactiflora Pall .

分子量

600.57

Formula

C30H32O13

CAS 号

172760-03-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Chevalone C

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Chevalone C 

Chevalone C 是一种半萜类真菌代谢产物,具有抗疟活性,IC50 值为 25 μg/mL。Chevalone C 对结肠癌 HCT116、肝癌 HepG2 和黑色素瘤 A375 细胞系具有抗增殖活性。

Chevalone C

Chevalone C Chemical Structure

CAS No. : 1318025-77-2

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生物活性

Chevalone C, a meroterpenoid fungal metabolite, shows antimalarial activity with IC50 value of 25.00 μg/mL. Chevalone C has anti-proliferative activity on colon HCT116, liver HepG2 and melanoma A375 cancer cell lines[1][2].

体外研究
(In Vitro)

Chevalone C (1, 10, 50, 100, 200 μM; 24 hours) exhibits a significant decrease of cell viability in HepG2, HCT116 and HT29 cell lines (ic50=153 μM, 190 μM, 98 μM)[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

456.61

Formula

C28H40O5

CAS 号

1318025-77-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Sasiphimol Sawadsitang, et al. Antimalarial and cytotoxic constituents of Xylaria cf. cubensis PK108. Nat Prod Res. 2015;29(21):2033-6.

    [2]. M Prata-Sena, et al.  Cytotoxic activity of Secondary Metabolites from Marine-derived Fungus Neosartorya siamensis in Human Cancer Cells. Phytother Res. 2016 Nov;30(11):1862-1871.

Caesalmin B

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Caesalmin B 

Caesalmin B 是一种从 Caesalpinia minax 中分离出来呋喃二萜类内酯。Caesalmin B 具有抗病毒活性。

Caesalmin B

Caesalmin B Chemical Structure

CAS No. : 352658-23-2

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生物活性

Caesalmin B is a furanoditerpenoid lactone isolated from Caesalpinia minax. Caesalmin B exhibits antiviral activity[1][2].

分子量

388.45

Formula

C22H28O6

CAS 号

352658-23-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jiang RW, et, al. Molecular structures and antiviral activities of naturally occurring and modified cassane furanoditerpenoids and friedelane triterpenoids from Caesalpinia minax. Bioorg Med Chem. 2002 Jul;10(7):2161-70.

    [2]. Kalauni SK, et, al. Cassane- and norcassane-type diterpenes of Caesalpinia crista from Myanmar. J Nat Prod. 2004 Nov; 67(11): 1859-63.

Wilforlide B

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Wilforlide B 

Wilforlide B 是一种天然的萜类化合物,具有抗癌活性。

Wilforlide B

Wilforlide B Chemical Structure

CAS No. : 84104-70-1

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生物活性

Wilforlide B, a natural norditerpenoid, possesses anti-tumor activity in human cancer cells[1].

分子量

452.67

Formula

C30H44O3

CAS 号

84104-70-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Xiao-Wei Zhang, et al. Cytotoxic Triterpenoids from the Stalks of Microtropis triflora. Chem Biodivers. 2017 Jul;14(7).