天然产物 天然产物苯丙素类 Phenylpropanoids
Sauchinone (Synonyms: 三白草酮) 纯度: 99.89%
Sauchinone 是一种非对映异构的木脂素,从 Saururus chinensis 中获得。Sauchinone 通过抑制 I-κBα 磷酸化和 p65 核易位来抑制 LPS 诱导的 iNOS,TNF-α 和 COX-2 表达。 Sauchinone 具有抗炎和抗氧化活性。
Sauchinone Chemical Structure
CAS No. : 177931-17-8
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5 mg | ¥800 | In-stock | |
10 mg | ¥1400 | In-stock | |
20 mg | ¥2300 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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Sauchinone 相关产品
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生物活性 |
Sauchinone is a diastereomeric lignan isolated from Saururus chinensis (Saururaceae). Sauchinone inhibits LPS-inducible iNOS, TNF-α and COX-2 expression through suppression of I-κBα phosphorylation and p65 nuclear translocation. Sauchinone has anti-inflammatory and antioxidant activity[1]. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
Sauchinone (1, 3, 10, 30μm; 6 hours) inhibits LPS-inducible increase in the iNOS mRNA in Raw264.7 cells[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
356.37 |
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Formula |
C20H20O6 |
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CAS 号 |
177931-17-8 |
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中文名称 |
三白草酮 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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溶解性数据 |
In Vitro:
DMSO : 22.73 mg/mL (63.78 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
*以上所有助溶剂都可在 MCE 网站选购。
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参考文献 |
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