Benzoyloxypaeoniflorin, isolated from the root of Paeonia suffruticosa, is a tyrosinase inhibitor against mushroom tyrosinase with IC50 of 0.453 mM. Benzoyloxypaeoniflorin is NF-κB Inhibitor and contributes to improving blood circulation through its inhibitory effect on both platelet aggregation and blood coagulation[1][2][3].
IC50 Target
IC50: 0.453 mM (Mushroom tyrosinase)[1] NF-κB[2]
分子量
600.57
Formula
C30H32O13
CAS 号
72896-40-3
中文名称
苯甲酰氧化芍药苷
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Ding HY, et al. Tyrosinase inhibitors isolated from the roots of Paeonia suffruticosa. J Cosmet Sci. 2009 May-Jun;60(3):347-52.
[2]. Lu Y, et al. The Screening Research of NF-κB Inhibitors from Moutan Cortex Based on Bioactivity-Integrated UPLC-Q/TOF-MS. Evid Based Complement Alternat Med. 2019 Mar 3;2019:6150357.
[3]. Koo YK, et al. Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. Pharmazie. 2010 Aug;65(8):624-8.
[1]. Xinfeng Zhao, et al. Quantitative and Qualitative Determination of Liuwei Dihuang Tablets by HPLC–UV-MS–MS. Journal of Chromatographic Science, Vol. 45, September 2007, 549-552
[2]. ZHANG Er-li, et al. Effects of Benzoylpaeoniflorin on apoptosis of Rats with Coronary Heart Diseases. Chinese Journal of Laboratory Diagnosis, 2011-04.