上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Caesalmin B
Caesalmin B 是一种从 Caesalpinia minax 中分离出来呋喃二萜类内酯。Caesalmin B 具有抗病毒活性。
Caesalmin B Chemical Structure
CAS No. : 352658-23-2
规格
是否有货
5 mg
询价
10 mg
询价
25 mg
询价
* Please select Quantity before adding items.
生物活性
Caesalmin B is a furanoditerpenoid lactone isolated from Caesalpinia minax. Caesalmin B exhibits antiviral activity[1][2].
分子量
388.45
Formula
C22H28O6
CAS 号
352658-23-2
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Jiang RW, et, al. Molecular structures and antiviral activities of naturally occurring and modified cassane furanoditerpenoids and friedelane triterpenoids from Caesalpinia minax. Bioorg Med Chem. 2002 Jul;10(7):2161-70.
[2]. Kalauni SK, et, al. Cassane- and norcassane-type diterpenes of Caesalpinia crista from Myanmar. J Nat Prod. 2004 Nov; 67(11): 1859-63.
Secologanin, a secoiridoid glucoside, is a pivotal terpenoid intermediate in the biosynthesis of biologically active monoterpenoid indole alkaloids such as reserpine, ajmaline, and vinblastine. Secologanin synthase (cytochrome P450 isoform CYP72A1) catalyzes the oxidative cleavage of loganin into Secologanin[1][2].
分子量
388.37
Formula
C17H24O10
CAS 号
19351-63-4
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder
-20deg;C
3 years
In solvent
-80deg;C
6 months
-20deg;C
1 month
参考文献
[1]. Inoue K. Yakugaku Zasshi. 2005;125(1):31-49. doi:10.1248/yakushi.125.31
[2]. Irmler S, et al. Indole alkaloid biosynthesis in Catharanthus roseus: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase. Plant J. 2000;24(6):797-804.
上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Chevalone C
Chevalone C 是一种半萜类真菌代谢产物,具有抗疟活性,IC50 值为 25 μg/mL。Chevalone C 对结肠癌 HCT116、肝癌 HepG2 和黑色素瘤 A375 细胞系具有抗增殖活性。
Chevalone C Chemical Structure
CAS No. : 1318025-77-2
规格
是否有货
100 mg
询价
250 mg
询价
500 mg
询价
* Please select Quantity before adding items.
生物活性
Chevalone C, a meroterpenoid fungal metabolite, shows antimalarial activity with IC50 value of 25.00 μg/mL. Chevalone C has anti-proliferative activity on colon HCT116, liver HepG2 and melanoma A375 cancer cell lines[1][2].
体外研究 (In Vitro)
Chevalone C (1, 10, 50, 100, 200 μM; 24 hours) exhibits a significant decrease of cell viability in HepG2, HCT116 and HT29 cell lines (ic50=153 μM, 190 μM, 98 μM)[2].
Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
456.61
Formula
C28H40O5
CAS 号
1318025-77-2
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Sasiphimol Sawadsitang, et al. Antimalarial and cytotoxic constituents of Xylaria cf. cubensis PK108. Nat Prod Res. 2015;29(21):2033-6.
[2]. M Prata-Sena, et al. Cytotoxic activity of Secondary Metabolites from Marine-derived Fungus Neosartorya siamensis in Human Cancer Cells. Phytother Res. 2016 Nov;30(11):1862-1871.