Hexa-N-acetylchitohexaose

天然产物 糖类和糖苷 Saccharides and Glycosides

Hexa-N-acetylchitohexaose;

Hexa-N-acetylchitohexaose 是作物抗病性的诱导剂,可诱导大豆木质化相关酶和抗氧化酶活性的增加。Hexa-N-acetylchitohexaose 是溶菌酶的底物。Hexa-N-acetylchitohexaose 具有抗肿瘤作用。

Hexa-N-acetylchitohexaose

Hexa-N-acetylchitohexaose Chemical Structure

CAS No. : 38854-46-5

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生物活性

Hexa-N-acetylchitohexaose is an inducer of disease resistance in crop plants, which could elicit an increase of lignification-related and antioxidative enzymes in soybean plants. Hexa-N-acetylchitohexaose is a substrate of lysozyme. Hexa-N-acetylchitohexaose shows antitumor effect[1][2][3].

体内研究
(In Vivo)

On sarcoma 180 solid tumor in ddY mice using lentinan, an antitumorβ-D-glucan, as the positive control. Hexa-N-acetylchitohexaose (100 mg/kg/day; 3 times; intravenous ) significantly inhibits the growth of this allogenic solid tumor, affording a high tumor growth-inhibition ratio (85%) at 7 days after tumor implantation[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1237.17

Formula

C48H80N6O31

CAS 号

38854-46-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Li K, et al. Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation. Biomed Res Int. 2017;2017:2486515.

    [2]. David C. Phillips. THE HEN EGG-WHITE LYSOZYME MOLECULE. Proc Natl Acad Sci U S A. 1967 Mar; 57(3): 483-495.

    [3]. Suzuki K, et al. Antitumor effect of hexa-N-acetylchitohexaose and chitohexaose. Carbohydr Res. 1986;151:403-408.