POT-4 TFA;(Synonyms: AL-78898A TFA)
POT-4 TFA (AL-78898A TFA),一种 Compstatin 衍生物,是补体因子 C3 激活的有效抑制剂。POT-4 TFA 可用于与年龄相关的黄斑变性的研究。
POT-4 TFA Chemical Structure
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100 mg |
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250 mg |
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500 mg |
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POT-4 TFA 的其他形式现货产品:
POT-4
生物活性 |
POT-4 TFA (AL-78898A TFA), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 TFA can be used for age-related macular degeneration research[1][2].
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体外研究 (In Vitro) |
A derivative of compstatin, a potent C3 inhibitor, POT-4 is a cyclic peptide that exhibits binding activity to C3, preventing cleavage to its active fragments C3a and C3b[2].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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运输条件 |
Room temperature in continental US; may vary elsewhere.
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis.
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参考文献 |
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[1]. S. Kaushal, et al. Complement C3 inhibitor POT-4: Clinical Safety of Intravitreal Administration. ARVO Annual Meeting Abstract, 2009 Apr.
[2]. Robyn Troutbeck, et al. Therapeutic targeting of the complement system in age-related macular degeneration: a review. Clin Exp Ophthalmol. Jan-Feb 2012;40(1):18-26.
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