天然产物 糖类和糖苷 Saccharides and Glycosides
Albiflorin;(Synonyms: 芍药内酯苷) 纯度: ge;98.0%
Albiflorin 是牡丹根中的主要成分,是一种具有神经保护作用的单萜糖苷。Albiflorin 还具有抗炎,抗氧化和缓解疼痛作用。
Albiflorin Chemical Structure
CAS No. : 39011-90-0
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
10;mM;*;1 mL in DMSO | ¥1650 | In-stock | |
5 mg | ¥1500 | In-stock | |
10 mg | ¥2550 | In-stock | |
50 mg | ; | 询价 | ; |
100 mg | ; | 询价 | ; |
* Please select Quantity before adding items.
Albiflorin 相关产品
bull;相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Immunology/Inflammation Compound Library
- Metabolism/Protease Compound Library
- NF-kappa;B Signaling Compound Library
- Stem Cell Signaling Compound Library
- Natural Product Library
- Anti-Aging Compound Library
- Antioxidants Compound Library
- Reprogramming Compound Library
- Macrocyclic Compound Library
- Glycoside Compound Library
- Oxygen Sensing Compound Library
- Ferroptosis Compound Library
- Terpenoids Library
- Pyroptosis Compound Library
- Orally Active Compound Library
- Traditional Chinese Medicine Monomer Library
- Neuroprotective Compound Library
- Anti-Blood Cancer Compound Library
- Anti-Parkinson’s Disease Compound Library
- Neurodegenerative Disease-related Compound Library
- Mitochondria-Targeted Compound Library
生物活性 |
Albiflorin, a major constituent contained in peony root, is a monoterpene glycoside with neuroprotective effects. Albiflorin also has anti-inflammatory, antioxidant and antinociceptive effects[1][2]. |
||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
体外研究 (In Vitro) |
Albiflorin (50-200 μM; pretreated for 3 hours; PC12 cells) treatment significantly ameliorates glutamate (Glu)-induced reduction of cell viability[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay[1]
Apoptosis Analysis[1]
Western Blot Analysis[1]
|
||||||||||||||||||||||||
体内研究 (In Vivo) |
Albiflorin (50 mg/kg; intraperitoneal injection; once a day; for 15 days; Wistar rats) treatment significantly increases the paw withdrawal threshold (PWT) on the 11th and 15th day after surgery in rats. Albiflorin could inhibit the activation of p38 MAPK pathway in spinal microglia and subsequent upregulated IL-1β and TNF-α. Albiflorin displays remarkable effects on inhibiting the activation of astrocytes, suppressing the overelevated expression of phosphorylation of c-JNK (p-JNK) in astrocytes, and decreasing the content of chemokine CXCL1 in the spinal cord[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
|
||||||||||||||||||||||||
分子量 |
480.46 |
||||||||||||||||||||||||
Formula |
C23H28O11 |
||||||||||||||||||||||||
CAS 号 |
39011-90-0 |
||||||||||||||||||||||||
中文名称 |
芍药内酯苷;白芍药苷;白芍苷 |
||||||||||||||||||||||||
运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||||||||||||||
储存方式 |
|
||||||||||||||||||||||||
溶解性数据 |
In Vitro:;
DMSO : ≥ 100 mg/mL (208.13 mM) H2O : 100 mg/mL (208.13 mM; Need ultrasonic) * “≥” means soluble, but saturation unknown. 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
|
||||||||||||||||||||||||
参考文献 |
|