标签归档：angiogenin

Angiogenin (108-122) (TFA)

发表于由

Angiogenin (108-122) (TFA); 纯度: 98.70%

Angiogenin (108-122) TFA 是一种血管生成素肽。

Angiogenin (108-122) (TFA)amp;;

Angiogenin (108-122) (TFA) Chemical Structure

规格 价格 是否有货 数量
1 mg ￥1300 In-stock
5 mg ￥5200 In-stock
10 mg ￥8100 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

Angiogenin (108-122) (TFA) 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Anti-Cancer Compound Library
  • Anti-Cardiovascular Disease Compound Library
  • Peptide Library

生物活性

Angiogenin (108-122) TFA is an angiogenin peptide.

体外研究
(In Vitro)

Angiogenin (108-122) effects on the ribonucleolytic activity of angiogenin using tRNA as substrate with 39% inhibition[1]. Angiogenin (108-122) acts as a therapeutic agent for the prophylaxis and/or treatment of cancer, an infectious disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, an autoimmune disease, or a heart and vascular disease[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1895.00

Formula

C80H126F3N25O25
Sequence

Glu-Asn-Gly-Leu-Pro-Val-His-Leu-Asp-Gln-Ser-Ile-Phe-Arg-Arg
Sequence Shortening

ENGLPVHLDQSIFRR
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : ≥ 50 mg/mL (26.39 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.5277 mL 2.6385 mL 5.2770 mL
5 mM 0.1055 mL 0.5277 mL 1.0554 mL
10 mM 0.0528 mL 0.2639 mL 0.5277 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Rybak SM, et al. C-terminal angiogenin peptides inhibit the biological and enzymatic activities of angiogenin. Biochem Biophys Res Commun. 1989 Jul 14;162(1):535-43.

    [2]. Dorian Bevec, et al. Therapeutic uses of angiogenin 108-122 and gluten exorphin a5. WO2009043455A2.

Angiogenin (108-122)

发表于由

Angiogenin (108-122);

Angiogenin (108-122) 是一种血管生成素肽。

Angiogenin (108-122)amp;;

Angiogenin (108-122) Chemical Structure

CAS No. : 112173-49-6

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

Angiogenin (108-122) 的其他形式现货产品:

Angiogenin (108-122) (TFA)

生物活性

Angiogenin (108-122) is an angiogenin peptide.

体外研究
(In Vitro)

Angiogenin (108-122) effects on the ribonucleolytic activity of angiogenin using tRNA as substrate with 39% inhibition[1]. Angiogenin (108-122) acts as a therapeutic agent for the prophylaxis and/or treatment of cancer, an infectious disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, an autoimmune disease, or a heart and vascular disease[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1780.98

Formula

C78H125N25O23
CAS 号

112173-49-6
Sequence

Glu-Asn-Gly-Leu-Pro-Val-His-Leu-Asp-Gln-Ser-Ile-Phe-Arg-Arg
Sequence Shortening

ENGLPVHLDQSIFRR
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Rybak SM, et al. C-terminal angiogenin peptides inhibit the biological and enzymatic activities of angiogenin. Biochem Biophys Res Commun. 1989 Jul 14;162(1):535-43.

    [2]. Dorian Bevec, et al. Therapeutic uses of angiogenin 108-122 and gluten exorphin a5. WO2009043455A2.