上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Bakkenolide B
Bakkenolide B 是从 petasites japonicas 叶片中分离出来的,具有抗过敏和抗炎作用。 Bakkenolide B 可用于研究哮喘。
Bakkenolide B Chemical Structure
CAS No. : 18455-98-6
规格 | 价格 | 是否有货 | |
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1 mg | ¥4600 | 询问价格 & 货期 | |
5 mg | ¥13200 | 询问价格 & 货期 |
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生物活性 |
Bakkenolide B is isolated from petasites japonicas leaves and has anti-allergic and anti-inflammatory effects. Bakkenolide B can be used for the study of asthma[1]. |
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体外研究 (In Vitro) |
Bakkenolide B (0-100 μg/ml; pretreatment 30 mins) inhibits antigen-induced β-hexosamidase release from RBL2H3 mast cells in a concentration-dependent manner[1].Bakkenolide B (0-10 μg/ml; 1 h later stimulated with LPS) strongly inhibits the gene inductions of inducible nitric oxide synthase and cyclooxygenase-2 in a concentration-dependent manner in mouse peritoneal macrophages[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot Analysis[1]
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体内研究 (In Vivo) |
Bakkenolide B (intraperitoneal injection; 1 mg/ml; 1 h before ovalbumin nebulization on days 28, 29, and 30) strongly inhibits the accumulation of eosinophils, macrophages, and lymphocytes to bronchoalveolar lavage fluid (BALF) in ovalbumin-induced asthma mice[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
390.47 |
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Formula |
C22H30O6 |
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CAS 号 |
18455-98-6 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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