标签归档：calmodulin

Cali-Bio CB500991.1mg Recombinant Human Calmodulin，Calmodulin重组人钙调蛋白 1mg

发表于由

上海金畔生物科技有限公司提供Cali-Bio CB500991.1mg Recombinant Human Calmodulin，Calmodulin重组人钙调蛋白 1mg，欢迎访问官网了解更多产品信息和订购

品牌 货号 产品名称 规格 价格

Cali-Bio CB500991.1mg Recombinant Human Calmodulin，Calmodulin重组人钙调蛋白 1mg 35089.00

Cali-Bio CB500991.50ug Recombinant Human Calmodulin，Calmodulin重组人钙调蛋白 50ug 3343.00

Cali-Bio CB500991.10ug Recombinant Human Calmodulin，Calmodulin重组人钙调蛋白 10ug 1300.00

Cali-Bio CB500990.100mg Recombinant Human Serum Albumin mammalian derived，rHSA哺乳动物来源的重组人血清白蛋白 100mg 24692.00

Cali-Bio CB500990.50mg Recombinant Human Serum Albumin mammalian derived，rHSA哺乳动物来源的重组人血清白蛋白 50mg 15595.00

Cali-Bio CB500990.10mg Recombinant Human Serum Albumin mammalian derived，rHSA哺乳动物来源的重组人血清白蛋白 10mg 5198.00

Cali-Bio CB500989.1mg Recombinant Human MHC class I chain-related gene B，MICB重组人MHC I类链相关基因B 1mg 107310.00

Cali-Bio CB500989.10ug Recombinant Human MHC class I chain-related gene B，MICB重组人MHC I类链相关基因B 10ug 3343.00

Cali-Bio CB500989.2ug Recombinant Human MHC class I chain-related gene B，MICB重组人MHC I类链相关基因B 2ug 1300.00

Cali-Bio CB500988.1mg Recombinant Human MHC class I chain-related gene A，MICA重组人MHC I类链相关基因A 1mg 107310.00

Cali-Bio CB500988.10ug Recombinant Human MHC class I chain-related gene A，MICA重组人MHC I类链相关基因A 10ug 3343.00

Cali-Bio CB500988.2ug Recombinant Human MHC class I chain-related gene A，MICA重组人MHC I类链相关基因A 2ug 1300.00

Cali-Bio CB500987.1mg Recombinant Human Non-Muscle Myosin-II Regulatory Light Chain，NMM重组人非肌肉肌球蛋白-II调节因子轻链 1mg 120677.00

Cali-Bio CB500987.10ug Recombinant Human Non-Muscle Myosin-II Regulatory Light Chain，NMM重组人非肌肉肌球蛋白-II调节因子轻链 10ug 3343.00

Cali-Bio CB500987.2ug Recombinant Human Non-Muscle Myosin-II Regulatory Light Chain，NMM重组人非肌肉肌球蛋白-II调节因子轻链 2ug 1300.00

Cali-Bio CB500986.1mg Recombinant Human Myosin Light Chain 1，MYL1重组人心肌肌球蛋白轻链LCII 1mg 77976.00

Cali-Bio CB500986.10ug Recombinant Human Myosin Light Chain 1，MYL1重组人心肌肌球蛋白轻链LCII 10ug 3343.00

Cali-Bio CB500986.2ug Recombinant Human Myosin Light Chain 1，MYL1重组人心肌肌球蛋白轻链LCII 2ug 1300.00

Cali-Bio CB500985.25ug Recombinant Human S100 Calcium Binding Protein A1，S100A1 25ug 14482.00

Cali-Bio CB500985.10ug Recombinant Human S100 Calcium Binding Protein A1，S100A1 10ug 7984.00

Calmodulin, from Bovine Brain 品牌：FUJIFILM Wako

发表于由

Calmodulin, from Bovine Brain

品牌：FUJIFILM Wako
CAS No.：73298-54-1
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

036-14591

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Calmodulin-Dependent Protein Kinase II(290-309) acetate

发表于由

Calmodulin-Dependent Protein Kinase II(290-309) acetate; 纯度: 98.97%

Calmodulin-Dependent Protein Kinase II (290-309) acetate 是有效的 CaMK 拮抗剂， 抑制抑制Ca2+/钙调蛋白依赖性蛋白激酶II的 IC50 值为52 nM。

Calmodulin-Dependent Protein Kinase II(290-309) acetateamp;;

Calmodulin-Dependent Protein Kinase II(290-309) acetate Chemical Structure

规格 价格 是否有货 数量
1 mg ￥2400 In-stock
5 mg ￥6500 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

Calmodulin-Dependent Protein Kinase II(290-309) acetate 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Calmodulin-Dependent Protein Kinase II (290-309) acetate is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II[1].

IC50 Target

IC50: 52 nM (calmodulin-dependent protein kinase II)[1].
体外研究
(In Vitro)

Peptide 290 to 309 is found to be a potent calmodulin antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase. Neither truncation from the amino terminus (peptide 296-309) nor extension in the carboxyl-terminal direction (peptide 294-319) markedly affects calmodulin binding, whereas shortening the peptide from the carboxyl terminus (peptide 290-302) or from both ends (peptide 295-304) results in the elimination of this activity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

2333.88

Formula

C105H189N31O26S
Sequence Shortening

LKKFNARRKLKGAILTTMLA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
参考文献

  • [1]. Payne ME, et al. Calcium/calmodulin-dependent protein kinase II. Characterization of distinct calmodulin binding and inhibitory domains. J Biol Chem. 1988 May 25;263(15):7190-5.

Calmodulin Binding Peptide 1

发表于由

Calmodulin Binding Peptide 1;

Calmodulin Binding Peptide 1 是一种来源于平滑肌肌球蛋白轻链激酶 (MLCK 肽) 的高亲和力 (pM) CaM 结合肽，能强烈抑制 IP3 诱导的 Ca2+ 释放。

Calmodulin Binding Peptide 1amp;;

Calmodulin Binding Peptide 1 Chemical Structure

CAS No. : 104041-80-7

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Calmodulin Binding Peptide 1 is a high affinity (pM) CaM-binding peptide derived from smooth muscle myosin light-chain kinase (MLCK peptide), which strongly inhibits IP3-induced Ca2+ release [1].

分子量

5301.10

Formula

C231H373N69O70S2
CAS 号

104041-80-7
Sequence

Gly-Val-Met-Pro-Arg-Glu-Glu-Thr-Asp-Ser-Lys-Thr-Ala-Ser-Pro-Trp-Lys-Ser-Ala-Arg-Leu-Met-Val-His-Thr-Val-Ala-Thr-Phe-Asn-Ser-Ile-Lys-Glu-Leu-Asn-Glu-Arg-Trp-Arg-Ser-Leu-Gln-Gln-Leu-Ala
Sequence Shortening

GVMPREETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. González-Andrade M, et al. Importance of the interaction protein-protein of the CaM-PDE1A and CaM-MLCK complexes in the development of new anti-CaM drugs. J Mol Recognit. 2013 Apr;26(4):165-74.

Calmodulin-Dependent Protein Kinase II (281-309)

发表于由

Calmodulin-Dependent Protein Kinase II (281-309);

Calmodulin-Dependent Protein Kinase II (281-309) 是钙/钙调素依赖蛋白激酶 II (CaM kinase II) 多肽片段。

Calmodulin-Dependent Protein Kinase II (281-309)amp;;

Calmodulin-Dependent Protein Kinase II (281-309) Chemical Structure

CAS No. : 116826-37-0

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Calmodulin-Dependent Protein Kinase II (281-309) is a peptide of calcium/calmodulin-dependent protein kinase II (CaM-kinase II)[1].

分子量

3374.06

Formula

C146H254N46O39S3
CAS 号

116826-37-0
Sequence

Met-His-Arg-Gln-Glu-Thr-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala
Sequence Shortening

MHRQETVDCLKKFNARRKLKGAILTTMLA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Chae YJ, et al. Block of Kv4.3 potassium channel by trifluoperazine independent of CaMKII. Neurosci Lett. 2014 Aug 22;578:159-64.

Calmodulin-Dependent Protein Kinase II (290-309)

发表于由

Calmodulin-Dependent Protein Kinase II (290-309);

Calmodulin-Dependent Protein Kinase II (290-309) 是有效的 CaMK 拮抗剂， 抑制抑制Ca2+/钙调蛋白依赖性蛋白激酶II的 IC50 值为52 nM。

Calmodulin-Dependent Protein Kinase II (290-309)amp;;

Calmodulin-Dependent Protein Kinase II (290-309) Chemical Structure

CAS No. : 115044-69-4

规格 价格 是否有货
1 mg ￥3300 询问价格 货期
5 mg ￥13000 询问价格 货期

* Please select Quantity before adding items.

Calmodulin-Dependent Protein Kinase II (290-309) 的其他形式现货产品:

Calmodulin-Dependent Protein Kinase II(290-309) acetate

生物活性

Calmodulin-Dependent Protein Kinase II (290-309) is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II[1].

IC50 Target

IC50: 52 nM (calmodulin-dependent protein kinase II)[1]
体外研究
(In Vitro)

Peptide 290 to 309 is found to be a potent calmodulin antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase. Neither truncation from the amino terminus (peptide 296-309) nor extension in the carboxyl-terminal direction (peptide 294-319) markedly affects calmodulin binding, whereas shortening the peptide from the carboxyl terminus (peptide 290-302) or from both ends (peptide 295-304) results in the elimination of this activity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

2273.83

Formula

C103H185N31O24S
CAS 号

115044-69-4
Sequence

Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala
Sequence Shortening

LKKFNARRKLKGAILTTMLA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Payne ME, et al. Calcium/calmodulin-dependent protein kinase II. Characterization of distinct calmodulin binding and inhibitory domains. J Biol Chem. 1988 May 25;263(15):7190-5.