Chlorahololide C

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Chlorahololide C 

Chlorahololide C 是一种从 Chloranthus holostegius 中分离得到林丹倍半萜类二聚体。Chlorahololide C 是一种有效和选择性的钾通道阻滞剂,IC50 值为 3.6 μM。

Chlorahololide C

Chlorahololide C Chemical Structure

CAS No. : 1007859-25-7

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC50 of 3.6 μM[1].

IC50 & Target

IC50: 3.6 μM (potassium channel)[1]

体外研究
(In Vitro)

Chlorahololide C (0.1-100 μM) inhibits the delayed rectifier K+ current (IK) in rat dissociated hippocampal neurons, with an IC50 of 3.6 μM[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

576.63

Formula

C33H36O9

CAS 号

1007859-25-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Yang SP, et, al. Chlorahololides C-F: a new class of potent and selective potassium channel blockers from Chloranthus holostegius. Tetrahedron. 2008 Feb; 64(9):2027-2034.