标签归档：cp

PCR-2CP-RT-C-美国Axygen 0.2ml八排平盖

发表于由
  • 型号 PCR-2CP-RT-C
  • 品牌 爱思进
  • 【简单介绍】
    品牌 其他品牌

    美国Axygen 0.2ml八排平盖，Axygen 1 x 8条扁平PCR超透明薄壁盖；设计用于容纳8条PCR试管和96孔PCR微孔板；

    产品简介：
    产品品牌：Axygen
    产品名称：Axygen PCR-2CP-RT-C 0.2ml荧光定量八排平盖
    产品货号：PCR-2CP-RT-C 
    产品规格：125排/包；10包/箱
    保存温度：室温
    爱思进Axygen PCR-2CP-RT-C 0.2ml荧光定量八排平盖，产品说明：
    •Axygen PCR-2CP-RT-C 0.2ml荧光定量八排平盖；
    •Axygen 1 x 8条扁平PCR超透明薄壁盖；设计用于容纳8条PCR试管和96孔PCR微孔板； 
    •专为实时PCR设计；
    •不含RNase / DNase、无热原、非无菌荧光，发光和实时PCR的理想选择；
    •透光率提高75％；
    •用99.9％的纯净聚丙烯制造。

    美国Axygen 0.2ml八排平盖  PCR-2CP-RT-C

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610CP

发表于由

610CP;

610CP 是激动蛋白微丝的探针，其absorption λmax 和 fluor λmax 值分别为 609 nM 和 634 nM。

610CPamp;;

610CP Chemical Structure

CAS No. : 1877282-17-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

610CP, a carbopyronine derivative, could be used to label actin filaments. The absorption λmax and fluor λmax values are 609 nM and 634 nM, respectively[1].

分子量

456.53

Formula

C28H28N2O4
CAS 号

1877282-17-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Vladimir N Belov, et al. Synthesis of Fluorescent Jasplakinolide Analogues for Live-Cell STED Microscopy of Actin. J Org Chem. 2020 Jun 5;85(11):7267-7275.

CP-BP-SFAC

发表于由

CP-BP-SFAC;

CP-BP-SFAC 是一种发光分子。CP-BP-SFAC 在纯薄膜中表现出强烈的天蓝色延迟荧光。

CP-BP-SFACamp;;

CP-BP-SFAC Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

CP-BP-SFAC is a luminogenic molecule. CP-BP-SFAC exhibits strong sky-blue delayed fluorescence in neat films[1].

分子量

676.80

Formula

C50H32N2O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Fu Y, et al. Boosting external quantum efficiency to 38.6% of sky-blue delayed fluorescence molecules by optimizing horizontal dipole orientation. Sci Adv. 2021 Oct 22;7(43):eabj2504.

Saponin CP6(Synonyms: Clematoside S; Prosapogenin CP6)

发表于由

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Saponin CP6 (Synonyms: Clematoside S; Prosapogenin CP6)

Saponin CP6 是一种来自 Clematis grata 根部的三萜类化合物。

Saponin CP6(Synonyms: Clematoside S; Prosapogenin CP6)

Saponin CP6 Chemical Structure

CAS No. : 72629-76-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Saponin CP6 is a triterpenoid compound from the roots of Clematis grata[1].

分子量

883.07

Formula

C46H74O16
CAS 号

72629-76-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Sati OP, et al. Clematoside-S, a triterpenoid saponin from the roots of Clematis grata. Phytochemistry. 1990;29(11):3676-3678.

Axygen 八排管盖PCR-2CP-RT-C PCR-2CP-RT-C

发表于由

Axygen 八排管盖PCR-2CP-RT-C

Axygen 八排管盖PCR-2CP-RT-C PCR薄壁管 Axygen 八排管盖PCR-2CP-RT-C 8连排，透明，125排/盒,10盒/箱

Axygen 八排管盖PCR-2CP-RT-C

PCR-0208-C爱思进0.2mlPCR荧光定量八联排管

PCR-2CP-RT-C爱思进0.2mlPCR荧光定量八联排管盖

Axygen爱思进0.2mL聚丙烯PCR管带，8管/条，各种颜色，非无菌（产品编号PCR-0208-C）

Axygen爱思进0.2mL薄壁8条PCR PCR管，可提供各种颜色，适用于各种热循环仪。超薄和*的壁厚允许精que的热传递，即使插入帽确保紧配合以防止蒸发。

● 认证的RNase-/DNase-free

● 无致热

● 非无菌

● 盖单独出售

● 制造与99.9％纯纯聚丙烯

爱思进AXYGEN现为康宁Corning旗下品牌。

 

货号

产品名称

产品规格


PCR-0208-C 

PCR薄壁管

0.2mL，8连排，透明，125排/盒,10盒/箱

PCR-2CP-RT-C 八联排管盖  

AMY-101(Synonyms: Cp40)

发表于由

AMY-101;(Synonyms: Cp40)

AMY-101 (Cp40) 是补体 C3 的肽类抑制剂 (KD = 0.5 nM)，可抑制非人类灵长类动物自然发生的牙周炎。AMY-101 (Cp40) 在 COVID-19 重症肺炎合并全身超炎症模型中具有良好的抗炎活性。

AMY-101amp;;(Synonyms: Cp40)

AMY-101 Chemical Structure

CAS No. : 1427001-89-5

规格 价格 是否有货
1 mg ￥4000 询问价格 货期
5 mg ￥9800 询问价格 货期
10 mg ￥16500 询问价格 货期

* Please select Quantity before adding items.

AMY-101 的其他形式现货产品:

AMY-101 TFA AMY-101 acetate

生物活性

AMY-101 (Cp40), a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM), inhibits naturally occurring periodontitis in non-human primates (NHPs). AMY-101 (Cp40) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation[1][2].

IC50 Target

KD: 0.5 nM (C3)[1].
体内研究
(In Vivo)

AMY-101 can improve the periodontal condition of NHPs with natural chronic periodontitis[1].
AMY-101 can induce a long-lasting anti-inflammatory effect[1].
AMY-101 (4 mg/kg bodyweight, subcutaneous injection. once per 24 hr for a total of 28 days) causes a significant and long-lasting reduction in PPD, an index that measures tissue destruction[1].
AMY-101 (Cp40, 1 mg/kg, sc, injection every 12 h, daily, 7 or 14 days) attenuates fibrosis and infiltration of inflammatory cells in UUO-induced renal fibrosis[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Fifteen adult male cynomolgus monkeys (Macaca fascicularis) (7-15 years old; 5.0-7.6 kg body weight)[1].
Dosage: 0.1 mg/site; 50 μL of 2 mg/mL solution.
Administration: Injected locally. (Either three times per week or once a week for 6 weeks followed by a 6-week follow-up period without treatment.)
Result: Does not cause irritation in healthy gingiva.
Animal Model: UUO and sham-operated mice[3].
Dosage: 1 mg/kg.
Administration: Subcutaneous injection every 12 h, daily, 7 or 14 days.
Result: 1 mg/kg Cp40 had much less severe interstitial fibrosis than control peptide-injected mice.

Clinical Trial

分子量

1789.11

Formula

C83H117N23O18S2
CAS 号

1427001-89-5
Sequence Shortening

YICV-{Trp(Me)}-QDW-{Sar}-AHRC-{N(Me)Ile}-NH2 (Disulfide bridge:Cys3-Cys13)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Kajikawa T, et al. Safety and Efficacy of the Complement Inhibitor AMY-101 in a Natural Model of Periodontitis in Non-human Primates. Mol Ther Methods Clin Dev. 2017 Aug 18;6:207-215.

    [2]. Mastaglio S, et al. The first case of COVID-19 treated with the complement C3 inhibitor AMY-101. Clin Immunol. 2020 Apr 29:108450

    [3]. Yanyan Liu, et al. Complement C3 Produced by Macrophages Promotes Renal Fibrosis via IL-17A Secretion. Front Immunol. 2018 Oct 22;9:2385.

Saponin CP4(Synonyms: Prosapogenin CP4)

发表于由

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Saponin CP4 (Synonyms: Prosapogenin CP4)

Saponin CP4 是一种缺乏 23-OH 的齐墩果酸衍生物。Saponin CP4 无生长抑制作用。

Saponin CP4(Synonyms: Prosapogenin CP4)

Saponin CP4 Chemical Structure

CAS No. : 75799-18-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Saponin CP4 is an oleanolic acid derivative which lacks a 23-OH. Saponin CP4 shows no growth inhibition[1].

分子量

867.07

Formula

C46H74O15
CAS 号

75799-18-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Yukiyoshi Tamura, et al. Application of Saponin-Containing Plants in Foods and Cosmetics.