标签归档：cx

CX-5461 品牌：SynKinase

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CX-5461

品牌：SynKinase
CAS No.：1138549-36-6
储存条件：+4℃
纯度：≥95%
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

SYN-3031-M050

 – 50 mg –

CX-5461 品牌：SynKinase

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

CX-5461 品牌：SynKinase

发表于由

CX-5461

品牌：SynKinase
CAS No.：1138549-36-6
储存条件：+4℃
纯度：≥95%
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

SYN-3031-M100

 – 100 mg –

CX-5461 品牌：SynKinase

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

CX-4945 品牌：SynKinase

发表于由

CX-4945

品牌：SynKinase
CAS No.：1009820-21-6
储存条件：-20℃
纯度：≥95%
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

SYN-1109-M001

 – 1 mg –

CX-4945 品牌：SynKinase

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

CX-4945 品牌：SynKinase

发表于由

CX-4945

品牌：SynKinase
CAS No.：1009820-21-6
储存条件：-20℃
纯度：≥95%
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

SYN-1109-M005

 – 5 mg –

CX-4945 品牌：SynKinase

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

CX-4945 品牌：SynKinase

发表于由

CX-4945

品牌：SynKinase
CAS No.：1009820-21-6
储存条件：-20℃
纯度：≥95%
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

SYN-1109-M010

 – 10 mg –

CX-4945 品牌：SynKinase

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

CX-4945 品牌：SynKinase

发表于由

CX-4945

品牌：SynKinase
CAS No.：1009820-21-6
储存条件：-20℃
纯度：≥95%
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

SYN-1109-M050

 – 50 mg –

CX-4945 品牌：SynKinase

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

CX-4945 品牌：SynKinase

发表于由

CX-4945

品牌：SynKinase
CAS No.：1009820-21-6
储存条件：-20℃
纯度：≥95%
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

SYN-1109-M100

 – 100 mg –

CX-4945 品牌：SynKinase

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Gap19

发表于由

Gap19;

Gap19 是一种衍生自 Cx43 细胞质环 (CL) 九个氨基酸的肽，一种有效的，选择性连接蛋白 43 (Cx43) 半通道阻滞剂。Gap19 可以防止 C 末端 (CT) 与 CL 的分子内相互作用。Gap19 不阻断 GJ 通道或 Cx40/pannexin-1 半通道。Gap19 对心肌具有保护作用。

Gap19amp;;

Gap19 Chemical Structure

CAS No. : 1507930-57-5

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

Gap19 的其他形式现货产品:

Gap19 TFA

生物活性

Gap19, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 has protective effects against myocardial[1][2].

IC50 Target

Cx43 Hemichannel[1]
体外研究
(In Vitro)

Gap19 (250 μM; for 30 min ) decreases mitochondrial potassium uptake[1].
Gap19 (400 μM) inhibits unitary hemichannel currents in HeLa-Cx43 cells[2].
Gap19 (100 μM) inhibits hemichannel unitary currents in ventricular cardiomyocytes[2].
Gap19 (250 μM, 30 min) protects against myocardial ischemia/reperfusion injury in vitro and in vivo[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

Gap19 (iv; 25 mg/kg; 10 min before ligation) significantly reduces the infarct size by approximately one-fifth[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57/BL6 mice[2]
Dosage: 25 mg/kg
Administration: IV; 10 min before ligation
Result: Significantly reduced the infarct size by approximately one-fifth.

分子量

1161.44

Formula

C55H96N14O13
CAS 号

1507930-57-5
Sequence Shortening

KQIEIKKFK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Boengler K, et al. Connexin 43 impacts on mitochondrial potassium uptake. Front Pharmacol. 2013 Jun 6;4:73.

    [2]. Wang N, et al. Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury. Basic Res Cardiol. 2013 Jan;108(1):309.

Jena Bioscience CC-CX100 Cryo Express Dry Shipper 1pc.

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上海金畔生物科技有限公司提供Jena Bioscience CC-CX100 Cryo Express Dry Shipper 1pc.，欢迎访问官网了解更多产品信息和订购

品牌 货号 产品名称 规格 价格

Jena Bioscience CC-CX100 Cryo Express Dry Shipper 1pc. 19890.00

Jena Bioscience CC-CSM003-0005A Puck Support 1pc. 7290.00

Jena Bioscience CC-CSM003-0001A SPINE Puck 1pc. 7968.00

Jena Bioscience CC-330-22 Cryo Shutter for Cryostream 700 Systems 1Kit 15473.00

Jena Bioscience CC-330-19LTD Cryo Shutter for Cryojet Systems with limited space 1Kit 15473.00

Jena Bioscience CC-330-19 Cryo Shutter for Cryojet Systems 1Kit 15473.00

Jena Bioscience BU-126 SDS PAGE Sample Buffer – 2x conc. 3 x 10ml 456.00

Jena Bioscience BU-125S Tris-HCl Buffer 1 M pH 7.5 100ml 480.00

Jena Bioscience BU-125L Tris-HCl Buffer 1 M pH 7.5 1l 960.00

Jena Bioscience BU-124S-85 Tris-HCl Buffer 1 M pH 8.5 100ml 468.00

Jena Bioscience BU-124S-80 Tris-HCl Buffer 1 M pH 8.0 100ml 480.00

Jena Bioscience BU-124S-70 Tris-HCl Buffer 1 M pH 7.0 100ml 480.00

Jena Bioscience BU-124L-85 Tris-HCl Buffer 1 M pH 8.5 1l 936.00

Jena Bioscience BU-124L-80 Tris-HCl Buffer 1 M pH 8.0 1l 960.00

Jena Bioscience BU-124L-70 Tris-HCl Buffer 1 M pH 7.0 1l 960.00

Jena Bioscience BU-122 Tris-Glycine Buffer – 10x conc. 1l 960.00

Jena Bioscience BU-121S-100 Tris-EDTA Buffer pH 7.6 – 100x conc. 100ml 699.00

Jena Bioscience BU-121S-1 Tris-EDTA Buffer pH 7.6 – 1x conc. 100ml 480.00

Jena Bioscience BU-121L-100 Tris-EDTA Buffer pH 7.6 – 100x conc. 1l 2706.00

Jena Bioscience BU-121L-1 Tris-EDTA Buffer pH 7.6 – 1x conc. 1l 960.00

MiTeGen TW-CX10-8C00 Shipping case for CX100 or CXR100

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上海金畔生物科技有限公司提供MiTeGen TW-CX10-8C00 Shipping case for CX100 or CXR100，欢迎访问官网了解更多产品信息和订购

品牌 货号 产品名称 规格 价格

MiTeGen TW-CX10-8C00 Shipping case for CX100 or CXR100 0.00

MiTeGen TW-CP70-9C18 CXR500 Spare Necktube Core 0.00

MiTeGen TW-1 Heavy duty serrated end tweezers 0.00

MiTeGen TW-033-8C00 Roller Base (HC34, HC35 & VHC35) 0.00

MiTeGen TPS-IN55 EchoTherm IN55 Chilling/Heating Incubator;    with fully programmable control  0.00

MiTeGen TPS-IN50 EchoTherm IN50 Chilling/Heating Incubator;    with non-programmable control  0.00

MiTeGen TPS-IN45 EchoTherm IN45 Chilling/Heating Incubator;    with fully programmable control  0.00

MiTeGen TPS-IN40 EchoTherm IN40 Chilling/Heating Incubator;    with non-programmable control  0.00

MiTeGen TPS-IN35 EchoTherm IN35 Chilling/Heating Incubator;    with fully programmable control  0.00

MiTeGen TPS-IN30 EchoTherm IN30 Chilling/Heating Incubator;    with non-programmable control  0.00

MiTeGen TPS-IIN30-300 Stacker, for IN30, IN40 0.00

MiTeGen T3SK-1 MicroTools™ Starter Kit #3 0.00

MiTeGen T3-L25-A1 T3-L25-A1 MicroTools for Measurements: Kit 3; 20 measuring tools with standard tips; 5 each of the Horizontal MicroRuler, Vertical MicroRuler, Large MicroProtractor, and Small MicroProtractor 0.00

MiTeGen T2SK-1 MicroTools™ Starter Kit #2 0.00

MiTeGen T2-L25-A1 T2-L25-A1 MicroTools for Manipulation: Kit 2; 20 durable and flexible tools for crystal manipulation. 0.00

MiTeGen T1SK-1 MicroTools™ Starter Kit #1 0.00

MiTeGen T1-L25-A1 T1-L25-A1 MicroTools for Manipulation: Kit 1; 20 durable and flexible tools for crystal manipulation. Updated 2013. 0.00

MiTeGen SMSK-2 Small Molecule Starter Kit with (20) B4 bases, 20 Dual Thickenss MicroMounts for Small Molecules ( (1) M2-L18SP-A2-SM), 1 tube Apiezon N Cryogenic vacuum grease 0.00

MiTeGen SMSK-1 Small Molecule Starter Kit with (10) B3S-R resuable bases and (10) CryoVials, 20 Dual Thickenss MicroMounts for Small Molecules ( (1) M2-L18SP-A2-SM), 1 tube Apiezon N Cryogenic vacuum grease 0.00

MiTeGen SCHK-1 Small Crystal Harvesting Kit; Contains 20 MicroMounts (M2-L18SP-A1), 20 MicroMesh (M3-L18SP-A1), 40 reusable bases (GB-B1A-R-40), 1.5 ml of LV CryoOil (LVCO-1), and one pair serrated-end tweezers (TW-1) 0.00