des-​Gln14-​Ghrelin TFA

des-​Gln14-​Ghrelin TFA;

des-Gln14-Ghrelin TFA 是生长激素促分泌受体的第二个内源性配体。des-Gln14-Ghrelin 可诱导 CHO-GHSR62 细胞中 [Ca2+]I 的上条,其 EC50 值为2.4 nM。

des-​Gln14-​Ghrelin TFAamp;;

des-​Gln14-​Ghrelin TFA Chemical Structure

规格 是否有货
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生物活性

des-Gln14-Ghrelin TFA is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca2+]i in CHO-GHSR62 cells, with an EC50 of 2.4 nM[1].

分子量

3300.69

Formula

C144H238F3N43O42

Sequence

Gly-Ser-{Oct-Ser}-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg

Sequence Shortening

GS-{Oct-Ser}-FLSPEHQKAQRKESKKPPAKLQPR

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. H Hosoda, et al. Purification and Characterization of Rat des-Gln14-Ghrelin, a Second Endogenous Ligand for the Growth Hormone Secretagogue Receptor. J Biol Chem. 2000 Jul 21;275(29):21995-2000.

[Des-His1,Glu9]-Glucagon amide

[Des-His1,Glu9]-Glucagon amide;

[Des-His1,Glu9]-Glucagon amide 是一种有效的胰高血糖素受体的肽拮抗剂,pA2 值为 7.2。 [Des-His1,Glu9]-Glucagon amide 在糖尿病的发病机理研究中有用。

[Des-His1,Glu9]-Glucagon amideamp;;

[Des-His1,Glu9]-Glucagon amide Chemical Structure

CAS No. : 110084-95-2

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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[Des-His1,Glu9]-Glucagon amide 的其他形式现货产品:

[Des-His1,Glu9]-Glucagon amide TFA

生物活性

[Des-His1,Glu9]-Glucagon amide is a potent and peptide antagonist of the glucagon receptor, with a pA2 of 7.2. [Des-His1,Glu9]-Glucagon amide is potentially useful in the study of the pathogenesis of diabetes[1].

IC50 Target

glucagon receptor[1]

分子量

3358.65

Formula

C148H221N41O47S

CAS 号

110084-95-2

Sequence

Ser-Gln-Gly-Thr-Phe-Thr-Ser-Glu-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2

Sequence Shortening

SQGTFTSEYSKYLDSRRAQDFVQWLMNT-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Unson CG, et, al. Biological activities of des-His1[Glu9]glucagon amide, a glucagon antagonist. Peptides. 1989 Nov; 10(6): 1171-7.

des-​Gln14-​Ghrelin

des-​Gln14-​Ghrelin;

des-Gln14-Ghrelin 是生长激素促分泌受体的第二个内源性配体。des-Gln14-Ghrelin 可诱导 CHO-GHSR62 细胞中 [Ca2+]i 的上条,其 EC50 值为2.4 nM。

des-​Gln14-​Ghrelinamp;;

des-​Gln14-​Ghrelin Chemical Structure

CAS No. : 293735-04-3

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca2+]i in CHO-GHSR62 cells, with an EC50 of 2.4 nM[1].

分子量

3186.67

Formula

C142H237N43O40

CAS 号

293735-04-3

Sequence

Gly-Ser-{Oct-Ser}-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg

Sequence Shortening

GS-{Oct-Ser}-FLSPEHQKAQRKESKKPPAKLQPR

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. H Hosoda, et al. Purification and Characterization of Rat des-Gln14-Ghrelin, a Second Endogenous Ligand for the Growth Hormone Secretagogue Receptor. J Biol Chem. 2000 Jul 21;275(29):21995-2000.

[Des-Tyr1]-Met-Enkephalin

[Des-Tyr1]-Met-Enkephalin;

[Des-Tyr1]-Met-Enkephalin 是一种四肽,是脑啡肽的降解产物。

[Des-Tyr1]-Met-Enkephalinamp;;

[Des-Tyr1]-Met-Enkephalin Chemical Structure

CAS No. : 61370-88-5

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

[Des-Tyr1]-Met-Enkephalin, a tetrapeptide, is a degradationproduct of enkephalins[1].

体外研究
(In Vitro)

Tetrapeptide H-gily-gly-phe-met-oh shows very littleactivity using the mouse[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

410.49

Formula

C18H26N4O5S

CAS 号

61370-88-5

Sequence Shortening

GGFM

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. J M Hambrook, et al. Mode of deactivation of the enkephalins by rat and human plasma and rat brain homogenates. Nature. 1976 Aug 26;262(5571):782-3.

Lys-[Des-Arg9]Bradykinin TFA

Lys-[Des-Arg9]Bradykinin TFA; 纯度: 99.48%

Lys-[Des-Arg9]Bradykinin TFA 是一种天然存在的激肽,是一种有效且高度选择性的缓激肽 B1 受体激动剂,对人,小鼠和兔子的 B1 受体的 Ki 值为 0.12 nM,1.7 nM 和 0.23 nM。Lys-[Des-Arg9]Bradykinin TFA 对 B2 受体的抑制活性较低。

Lys-[Des-Arg9]Bradykinin TFAamp;;

Lys-[Des-Arg9]Bradykinin TFA Chemical Structure

规格 价格 是否有货 数量
10;mM;*;1 mL in DMSO ¥2520 In-stock
5 mg ¥1200 In-stock
10 mg ¥2000 In-stock
50 mg ¥5000 In-stock
100 mg ; 询价 ;
200 mg ; 询价 ;

* Please select Quantity before adding items.

Lys-[Des-Arg9]Bradykinin TFA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • GPCR/G Protein Compound Library
  • Immunology/Inflammation Compound Library
  • Neurotransmitter Receptor Compound Library
  • Targeted Diversity Library
  • Peptide Library

生物活性

Lys-[Des-Arg9]Bradykinin TFA, a naturally occurring kinin, is a potent and highly selective bradykinin B1 receptor agonist with a Ki of 0.12 nM, 1.7 nM and 0.23 nM for human, mouse and rabbit B1 receptors, respectively. Lys-[Des-Arg9]Bradykinin TFA has low inhibitory activity on B2 receptors[1][2].

体外研究
(In Vitro)

Lys-[Des-Arg9]Bradykinin is formed by the proteolytic cleavage of bradykinin, exerts its effects through bradykinin B1 receptor (B1R)[1].
Lys-[Des-Arg9]Bradykinin (Lda-BK; 10 μM) enhances the secretion of IL-12p70 and inhibits the secretion of IL-12p40 by mature hMo-DCs. Pretreatment with Lys-[Des-Arg9]Bradykinin treatment reduces the migration of mature hMo-DCs toward medium alone, suggesting that Lys-[Des-Arg9]Bradykinin may inhibit the chemokinesis of mature hMo-DCs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Lys-[Des-Arg9]Bradykinin (1 μg; intra-artenal injection; New Zealand White rabbits) treatment reduces peripheral vascular resistance in LPS-induced rabbits, but the effect is brief (T1/2 is 118-195 s)[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1146.22

Formula

C52H74F3N13O13

Sequence Shortening

KRPPGFSPF

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro:;

DMSO : 110 mg/mL (95.97 mM; Need ultrasonic)

H2O : 50 mg/mL (43.62 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.8724 mL 4.3622 mL 8.7243 mL
5 mM 0.1745 mL 0.8724 mL 1.7449 mL
10 mM 0.0872 mL 0.4362 mL 0.8724 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.75 mg/mL (2.40 mM); Clear solution

    此方案可获得 ≥ 2.75 mg/mL (2.40 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 27.5 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂:;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.75 mg/mL (2.40 mM); Clear solution

    此方案可获得 ≥ 2.75 mg/mL (2.40 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 27.5 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 3.

    请依序添加每种溶剂:;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.75 mg/mL (2.40 mM); Clear solution

    此方案可获得 ≥ 2.75 mg/mL (2.40 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 27.5 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献
  • [1]. Rosalind Gulliver, et al. Lys-des[Arg9]-bradykinin alters migration and production of interleukin-12 in monocyte-derived dendritic cells. Am J Respir Cell Mol Biol. 2011 Sep;45(3):542-9.

    [2]. L M Fredrik Leeb-Lundberg, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.

    [3]. G Drapeau, et al. Hypotensive effects of Lys-des-Arg9-bradykinin and metabolically protected agonists of B1 receptors for kinins. J Pharmacol Exp Ther. 1991 Dec;259(3):997-1003.

[Des-His1,Glu9]-Glucagon amide TFA

[Des-His1,Glu9]-Glucagon amide TFA; 纯度: 98.29%

[Des-His1,Glu9]-Glucagon amide TFA 是一种有效的胰高血糖素受体的肽拮抗剂,pA2 值为 7.2。 [Des-His1,Glu9]-Glucagon amide TFA 在糖尿病的发病机理研究中有用。

[Des-His1,Glu9]-Glucagon amide TFAamp;;

[Des-His1,Glu9]-Glucagon amide TFA Chemical Structure

规格 价格 是否有货 数量
1 mg ¥2800 In-stock
5 mg ¥8500 In-stock
10 mg ¥13500 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

[Des-His1,Glu9]-Glucagon amide TFA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

[Des-His1,Glu9]-Glucagon amide TFA is a potent and peptide antagonist of the glucagon receptor, with a pA2 of 7.2. [Des-His1,Glu9]-Glucagon amide TFA is potentially useful in the study of the pathogenesis of diabetes[1].

IC50 Target

glucagon receptor[1]

分子量

3472.67

Formula

C150H222F3N41O49S

Sequence

Ser-Gln-Gly-Thr-Phe-Thr-Ser-Glu-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2

Sequence Shortening

SQGTFTSEYSKYLDSRRAQDFVQWLMNT-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Unson CG, et, al. Biological activities of des-His1[Glu9]glucagon amide, a glucagon antagonist. Peptides. 1989 Nov; 10(6): 1171-7.

[Des-Arg9]-Bradykinin acetate(Synonyms: [Des-Arg9]-缓激肽醋酸盐)

[Des-Arg9]-Bradykinin acetate (Synonyms: [Des-Arg9]-缓激肽醋酸盐) 纯度: 96.90%

[Des-Arg9]-Bradykinin acetate 是缓激肽 B1 受体 (Bradykinin B1 receptor) 激动剂,对 B1 受体的选择性高于 B2 受体。

[Des-Arg9]-Bradykinin acetate (Synonyms: [Des-Arg9]-缓激肽醋酸盐)

[Des-Arg9]-Bradykinin acetate Chemical Structure

CAS No. : 23827-91-0

规格 价格 是否有货 数量
5 mg ¥550 In-stock
10 mg ¥880 In-stock
25 mg ¥1900 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

[Des-Arg9]-Bradykinin acetate 相关产品

相关化合物库:

  • Bioactive Compound Library Plus
  • Peptidomimetic Library
  • Peptide Library

生物活性

[Des-Arg9]-Bradykinin acetate is a Bradykinin B1 receptor agonist that displays selectivity for B1 over B2 receptors.

IC50 & Target

Bradykinin B1 receptor[1]

体外研究
(In Vitro)

[Des-Arg9]-Bradykinin acetate is a Bradykinin(B1) receptor agonist. The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

964.07

Formula

C46H65N11O12

CAS 号

23827-91-0

Sequence

Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe

Sequence Shortening

RPPGFSPF

中文名称

[Des-Arg9]-缓激肽醋酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

H2O : 100 mg/mL (103.73 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.0373 mL 5.1863 mL 10.3727 mL
5 mM 0.2075 mL 1.0373 mL 2.0745 mL
10 mM 0.1037 mL 0.5186 mL 1.0373 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.

  • [1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.

[Des-Arg9]-Bradykinin(Synonyms: [Des-Arg9]-缓激肽)

[Des-Arg9]-Bradykinin;(Synonyms: [Des-Arg9]-缓激肽)

[Des-Arg9]-Bradykinin 是一种Bradykinin (B1) 受体激动剂,对 B1 受体选择性比B2 受体高。

[Des-Arg9]-Bradykininamp;;(Synonyms: [Des-Arg9]-缓激肽)

[Des-Arg9]-Bradykinin Chemical Structure

CAS No. : 15958-92-6

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

[Des-Arg9]-Bradykinin 的其他形式现货产品:

[Des-Arg9]-Bradykinin acetate

生物活性

[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.

IC50 Target

Bradykinin (B1) receptor[1]

体外研究
(In Vitro)

The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

904.02

Formula

C44H61N11O10

CAS 号

15958-92-6

Sequence

Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe

Sequence Shortening

RPPGFSPF

中文名称

[Des-Arg9]-缓激肽

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.