标签归档：dimethoxydihydrochalcone

4′,2-Dihydroxy-4,6-dimethoxydihydrochalcone

发表于由

天然产物 天然产物苯丙素类 Phenylpropanoids

4′,2-Dihydroxy-4,6-dimethoxydihydrochalcone 

4′,2-Dihydroxy-4,6-dimethoxydihydrochalcone 是一种雌激素 (estrogen) 激动剂，对牛子宫雌激素受体具有结合亲和力，IC50 为 15 μM [1] 。

4

4′,2-Dihydroxy-4,6-dimethoxydihydrochalcone Chemical Structure

CAS No. : 151752-07-7

规格 是否有货
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生物活性

4′,2-Dihydroxy-4,6-dimethoxydihydrochalcone, an estrogen agonist, shows binding affinity for bovine uterine estrogen receptor with an IC5050 of 15 μM[1].

IC50 & Target[1]

Estrogen receptor

 

体外研究
(In Vitro)

4′,2-Dihydroxy-4,6-dimethoxydihydrochalcone stimulates the MCF-7 cell proliferation in a concentration dependent manner between 10 nM and 10 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

302.32

Formula

C17H18O5
CAS 号

151752-07-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. K Ichikawa, et al. Retrodihydrochalcones and homoisoflavones isolated from Thai medicinal plant Dracaena loureiri and their estrogen agonist activity. Planta Med. 1997 Dec;63(6):540-3.