Green DND-26 用于标记酸性溶酶体以确定细胞分布。Green DND-26 是一种荧光染料，可对活细胞中的酸性隔室进行染色，并已被证明可选择性地积聚在肺泡 II 型 (AT2) 细胞的层状体中。
Green DND-26 Chemical Structure
CAS No. : 220524-71-0
规格
是否有货
100 mg
;
询价
;
250 mg
;
询价
;
500 mg
;
询价
;
* Please select Quantity before adding items.
生物活性
Green DND-26 is used to mark acidic lysosomes to determine the cellular distribution. Green DND-26 is a fluorescent dye that stains acidic compartments in live cells and has been shown to selectively accumulate in lamellar bodies in alveolar type II (AT2) cells in the lung[1][2].
分子量
362.23
Formula
C18H25BF2N4O
CAS 号
220524-71-0
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Sun B, et al. Acid-Activatable Transmorphic Peptide-Based Nanomaterials for Photodynamic Therapy. Angew Chem Int Ed Engl. 2020;59(46):20582-20588.
[2]. Van der Velden JL, et al. LysoTracker is a marker of differentiated alveolar type II cells. Respir Res. 2013;14(1):123. Published 2013 Nov 11.
LysoTracker Red (LysoTracker Red DND-99) 是一种多聚甲醛固定探针，可浓缩到细胞和组织的酸性隔间中。LysoTracker Red 是一种细胞死亡的指示剂，其方式与其他标准分析 (Annexin、末端 dUTP 缺口末端标记、尼罗蓝硫酸盐、中性红和吖啶橙) 类似。LysoTracker Red 是晚期内体和溶酶体的标志物。
LysoTracker Red Chemical Structure
CAS No. : 231946-72-8
规格
价格
是否有货
数量
1 mg
￥2800
In-stock
5 mg
￥6500
In-stock
10 mg
￥10500
In-stock
50 mg
;
询价
;
100 mg
;
询价
;
* Please select Quantity before adding items.
LysoTracker Red 相关产品
bull;相关化合物库:
Bioactive Compound Library Plus
生物活性
LysoTracker Red (LysoTracker Red DND-99) is a paraformaldehyde fixable probe that concentrates into acidic compartments of cells and tissues. LysoTracker Red is an indicator of cell death in a manner similar to other standard assays (Annexin, terminal dUTP nick end labeling, Nile blue sulfate, neutral red, and acridine orange)[1]. LysoTracker Red is a marker for late endosomes and lysosomes[2].
体外研究 (In Vitro)
Labeling of HepG2 cells with 100nM LysoTracker Red DND-99 aided examination of lysosome distribution[3].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
399.25
Formula
C20H24BF2N5O
CAS 号
231946-72-8
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder
-20deg;C
3 years
4deg;C
2 years
In solvent
-80deg;C
6 months
-20deg;C
1 month
参考文献
[1]. Price OT, et al. Quantitative fluorescence of 5-FU-treated fetal rat limbs using confocal laser scanning microscopy and Lysotracker Red. Cytometry A. 2003;53(1):9-21.
[2]. Pereira LC, et al. An autophagic process is activated in HepG2 cells to mediate BDE-100-induced toxicity. Toxicology. 2017;376:59-65.
[3]. Nagahama M, et al. Cellular vacuolation induced by Clostridium perfringens epsilon-toxin. FEBS J. 2011;278(18):3395-3407.
