天然产物 糖类和糖苷 Saccharides and Glycosides
Engeletin;(Synonyms: 黄杞苷) 纯度: 99.72%
Engeletin 是从 hymenaea martiana 中得到的黄酮苷类物质,能够抑制 NF-κB 信号通路的激活,具有抗炎、缓解疼痛、利尿、消肿、抗菌等作用。
Engeletin Chemical Structure
CAS No. : 572-31-6
规格 | 价格 | 是否有货 | 数量 |
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10;mM;*;1 mL in DMSO | ¥660 | In-stock | |
5 mg | ¥600 | In-stock | |
10 mg | ¥950 | In-stock | |
25 mg | ¥2100 | In-stock | |
50 mg | ¥3600 | In-stock | |
100 mg | ¥6400 | In-stock | |
200 mg | ; | 询价 | ; |
500 mg | ; | 询价 | ; |
* Please select Quantity before adding items.
Engeletin 相关产品
bull;相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Anti-Infection Compound Library
- Immunology/Inflammation Compound Library
- NF-kappa;B Signaling Compound Library
- Stem Cell Signaling Compound Library
- Natural Product Library
- Anti-Aging Compound Library
- Antioxidants Compound Library
- Differentiation Inducing Compound Library
- Diabetes Related Compound Library
- Glycoside Compound Library
- Oxygen Sensing Compound Library
- Phenols Library
- Pyroptosis Compound Library
- Traditional Chinese Medicine Monomer Library
- Flavonoids Library
- Anti-Breast Cancer Compound Library
- Anti-Pancreatic Cancer Compound Library
- Anti-Blood Cancer Compound Library
- Anti-Obesity Compound Library
- Transcription Factor Targeted Library
- Food-Sourced Compound Library
- Anti-Liver Cancer Compound Library
生物活性 |
Engeletin is a flavanonol glycoside isolated from hymenaea martiana, inhibits NF-κB signaling-pathway activation, and possesses anti-inflammatory, analgesic, diuresis, detumescence, and antibiosis effects. |
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IC50 Target |
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体外研究 (In Vitro) |
Engeletin is a flavanonol glycoside isolated from hymenaea martiana, inhibits NF-κB signaling-pathway activation[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Engeletin (25, 50, 100 mg/kg, i.p.) markedly reduces LPS-increased myeloperoxidase activity in mice, activates NF-κB-pathway activation, decreases the production of inflammatory mediators (iNOS and COX-2), and suppresses the expression of TLR4-signaling downstream molecules such as MyD88, IRAK1, TRAF6, and TAK1 proteins[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
434.39 |
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Formula |
C21H22O10 |
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CAS 号 |
572-31-6 |
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中文名称 |
黄杞苷 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:;
DMSO : ≥ 100 mg/mL (230.21 mM) * “≥” means soluble, but saturation unknown. 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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Animal Administration [1] |
Mice[1] MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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参考文献 |
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