Polyethylene glycol 12-hydroxystearate

生化分析试剂 Biochemical Assay Reagents
Polyethylene glycol 12-hydroxystearate;

Polyethylene glycol 12-hydroxystearate, 一种 Macrogol 15 羟基硬脂酸酯,是一种通透性增强剂。

Polyethylene glycol 12-hydroxystearate

Polyethylene glycol 12-hydroxystearate Chemical Structure

CAS No. : 61909-81-7

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生物活性

Polyethylene glycol 12-hydroxystearate, a Macrogol 15 hydroxy stearate, is a permeability enhancer[1].

体外研究
(In Vitro)

Polyethylene glycol 12-hydroxystearate is used to increase the aqueous solubility of Biopharmaceutical Classification System (BCS) Class 2 and 4 lipophilic molecules. Polyethylene glycol 12-hydroxystearate has shown an enhancement in permeability of medium sized biological drugs across epithelia[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Formula

C20H40O4

CAS 号

61909-81-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture

溶解性数据
In Vitro:;

Ethanol : 100 mg/mL (Need ultrasonic)

参考文献
  • [1]. Shubber S, et al. Mechanism of mucosal permeability enhancement of CriticalSorb (Solutol HS15) investigated in vitro in cell cultures. Pharm Res. 2015 Feb;32(2):516-27.

Cell Assay
[1]

For both MTS and LDH cell viability assays, cells are seeded at a density of 1×104 cells on 96-well plates and cultured for a minimum of 24 h. Solutol HS-15 (in 25 mM HBSS:HEPES, pH 7.4) solutions are applied at concentrations above and below the critical micelle concentration (CMC) (0.01 mM to 20 mM) and cytotoxicity is determined using the MTS and LDH assays. 25 mM HBSS:HEPES is used as a negative control and Triton-X 100 (3 mM) as a positive control. Following 3 h incubation, the MTS reagent in media and LDH working solution are added to the cells and the cells are incubated for a further 3 h at 37°C[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献
  • [1]. Shubber S, et al. Mechanism of mucosal permeability enhancement of CriticalSorb (Solutol HS15) investigated in vitro in cell cultures. Pharm Res. 2015 Feb;32(2):516-27.

Polyethylene Glycol Mono-4-octylphenyl Ether

生化分析试剂 Biochemical Assay Reagents
Polyethylene Glycol Mono-4-octylphenyl Ether;

Polyethylene Glycol Mono-4-octylphenyl Ether 是一种低聚混合物,可用于生化研究。

Polyethylene Glycol Mono-4-octylphenyl Ether

Polyethylene Glycol Mono-4-octylphenyl Ether Chemical Structure

CAS No. : 9002-93-1

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Polyethylene Glycol Mono-4-octylphenyl Ether 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

Polyethylene Glycol Mono-4-octylphenyl Ether is an oligomeric blend that can be used for biochemical research[1].

Formula

C16H26O2

CAS 号

9002-93-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
参考文献
  • [1]. Chien-FongLu, et al. The Journal of Chemical Thermodynamics. 2019 Aug.135:215-224.

18:1 Ethylene Glycol

生化分析试剂 Biochemical Assay Reagents
18:1 Ethylene Glycol;

18:1 Ethylene Glycol 是一种用于递送药物的脂质体。

18:1 Ethylene Glycol

18:1 Ethylene Glycol Chemical Structure

CAS No. : 928-24-5

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生物活性

18:1 Ethylene Glycol is a liposome used to deliver drugs.

分子量

590.96

Formula

C38H70O4

CAS 号

928-24-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Polyethylene glycol monoisotridecyl ether

生化分析试剂 Biochemical Assay Reagents
Polyethylene glycol monoisotridecyl ether;

Polyethylene glycol monoisotridecyl ether 是一种表面活性剂。

Polyethylene glycol monoisotridecyl ether

Polyethylene glycol monoisotridecyl ether Chemical Structure

CAS No. : 9043-30-5

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生物活性

Polyethylene glycol monoisotridecyl ether is a surfactant[1].

Formula

(C2H4O)nC13H28O

CAS 号

9043-30-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
参考文献
  • [1]. Bruce J. et al. Sorption of Nonionic Surfactants on Sediment Materials. Environmental Science Technology 1997 31 (6), 1735-1741.

Sclareol glycol(Synonyms: 香紫苏二醇)

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Sclareol glycol (Synonyms: 香紫苏二醇)

Sclareol glycol 是氨氧化物的前体。Hyphozyma roseonigra ATCC 20624 是唯一报道的能够将香紫苏醇降解为 Sclareol Glycol 的主要产物的菌株。

Sclareol glycol(Synonyms: 香紫苏二醇)

Sclareol glycol Chemical Structure

CAS No. : 55881-96-4

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生物活性

Sclareol glycol is the precursor of ambroxide. Hyphozyma roseonigra ATCC 20624 was the only reported strain capable of degrading sclareol to the main product of sclareol glycol[1].

分子量

254.41

Formula

C16H30O2

CAS 号

55881-96-4

中文名称

香紫苏二醇

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Wang X, et al. Comparative proteomic analyses of Hyphozyma roseonigra ATCC 20624 in response to sclareol. Braz J Microbiol. 2019 Jan;50(1):79-84.