HCV-IN-4

发表于2023年11月9日由Whatman官网

HCV-IN-4;

HCV-IN-4 是一种有效、可口服的 HCV NS5A 抑制剂，可抑制 GT1a，GT2b，GT3a，GT1a Y93H 和 GT1a L31V 的增殖，EC₉₀ 值分别为 3 pM，0.3 nM，0.01 nM，0.5 nM 和 0.02 nM。

HCV-IN-4amp;;

HCV-IN-4 Chemical Structure

CAS No. : 2058080-25-2

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

* Please select Quantity before adding items.

生物活性	HCV-IN-4 is a potent and orally active HCV NS5A inhibitor, shows great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC₉₀s of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively^[1].
IC₅₀ Target	EC90: 3 pM (GT1a), 0.3 nM (GT2b), 0.01 nM (GT3a), 0.5 nM (GT1a Y93H), 0.02 nM (GT1a L31V)^[1]
分子量	956.07
Formula	C₅₂H₅₈FN₉O₈
CAS 号	2058080-25-2
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Yu W, et al. Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants. J Med Chem. 2016 Nov 23;59(22):10228-10243. Epub 2016 Nov 9.