Hosenkoside G(Synonyms: 凤仙萜四醇苷G)

天然产物 糖类和糖苷 Saccharides and Glycosides

Hosenkoside G;(Synonyms: 凤仙萜四醇苷G)

Hosenkoside G 是从凤仙花 (Impatiens Balsamina L.) 种子中分离得到的一种天然产物,具有抗肿瘤活性。

Hosenkoside G(Synonyms: 凤仙萜四醇苷G)

Hosenkoside G Chemical Structure

CAS No. : 160896-46-8

规格 价格 是否有货
1 mg ¥2290 询问价格 货期
5 mg ¥6860 询问价格 货期

* Please select Quantity before adding items.

生物活性

Hosenkoside G, a baccharane glycoside isolated from the seeds of Impatiens Balsamina L., possesses anti-tumor activity[1][2].

分子量

949.13

Formula

C47H80O19

CAS 号

160896-46-8

中文名称

凤仙萜四醇苷G

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Noboru SHOJI, et al. Hosenkosides F, G, H, I, J, and K, Novel Baccharane Glycosides from the Seeds of Impatiens balsamina. Chem Pharm Bull. 42(7) 1422-1426 (1944).

    [2]. Qian Wu, et al. Two new baccharane glycosides from seeds of Impatientis balsamina L. with in vitro growth inhibitory activity in human cancer A375 cells. Chemical Research in Chinese Universities. 2017 Oct.

Hosenkoside F(Synonyms: (+)-Hosenkoside F)

天然产物 糖类和糖苷 Saccharides and Glycosides

Hosenkoside F;(Synonyms: (+)-Hosenkoside F) 纯度: 98.39%

Hosenkoside F是从凤仙花种子中分离出的一种糖苷。

Hosenkoside F(Synonyms: (+)-Hosenkoside F)

Hosenkoside F Chemical Structure

CAS No. : 160896-45-7

规格 价格 是否有货 数量
5 mg ¥3900 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Hosenkoside F is a baccharane glycoside isolated from the seeds of impatiens balsamina.

分子量

949.13

Formula

C47H80O19

CAS 号

160896-45-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
参考文献
  • [1]. Yu X, et al. An LC-MS/MS method for simultaneous determination of hosenkoside A and hosenkoside K from Semen Impatientis in rat plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2017 Mar;31(3).

Hosenkoside B

天然产物 糖类和糖苷 Saccharides and Glycosides

Hosenkoside B; 纯度: 96.23%

Hosenkoside B是从凤仙花种子中分离出的一种糖苷。

Hosenkoside B

Hosenkoside B Chemical Structure

CAS No. : 156764-82-8

规格 价格 是否有货 数量
5 mg ¥2800 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Hosenkoside B is a baccharane glycoside isolated from the seeds of impatiens balsamina.

分子量

979.15

Formula

C48H82O20

CAS 号

156764-82-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
参考文献
  • [1]. Yu X, et al. An LC-MS/MS method for simultaneous determination of hosenkoside A and hosenkoside K from Semen Impatientis in rat plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2017 Mar;31(3).

Hosenkoside M(Synonyms: (+)-Hosenkoside M)

天然产物 糖类和糖苷 Saccharides and Glycosides

Hosenkoside M;(Synonyms: (+)-Hosenkoside M) 纯度: 99.71%

Hosenkoside M是从凤仙花种子中分离出的一种糖苷。

Hosenkoside M(Synonyms: (+)-Hosenkoside M)

Hosenkoside M Chemical Structure

CAS No. : 161016-51-9

规格 价格 是否有货 数量
5 mg ¥3900 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Hosenkoside M is a baccharane glycoside isolated from the seeds of impatiens balsamina.

分子量

1111.27

Formula

C53H90O24

CAS 号

161016-51-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
参考文献
  • [1]. Yu X, et al. An LC-MS/MS method for simultaneous determination of hosenkoside A and hosenkoside K from Semen Impatientis in rat plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2017 Mar;31(3).

Hosenkoside K

天然产物 糖类和糖苷 Saccharides and Glycosides

Hosenkoside K; 纯度: 98.61%

Hosenkoside K是从凤仙花种子中分离出的一种糖苷。

Hosenkoside K

Hosenkoside K Chemical Structure

CAS No. : 160896-49-1

规格 价格 是否有货 数量
5 mg ¥1900 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

Hosenkoside K 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Immunology/Inflammation Compound Library
  • Natural Product Library
  • Glycoside Compound Library

生物活性

Hosenkoside K is a baccharane glycoside isolated from the seeds of impatiens balsamina.

体内研究
(In Vivo)

The mean peak concentrations of hosenkoside K in rats after oral administration of total saponins of Semen Impatientis is 511.11±234.07 ng/mL, occurring at times of 0.46 h. The terminal half-lives of hosenkoside A is 4.96±1.75 h[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1141.29

Formula

C54H92O25

CAS 号

160896-49-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

DMSO : 100 mg/mL (87.62 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.8762 mL 4.3810 mL 8.7620 mL
5 mM 0.1752 mL 0.8762 mL 1.7524 mL
10 mM 0.0876 mL 0.4381 mL 0.8762 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (2.19 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.19 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂:;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (2.19 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.19 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 3.

    请依序添加每种溶剂:;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.19 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.19 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献
  • [1]. Yu X, et al. An LC-MS/MS method for simultaneous determination of hosenkoside A and hosenkoside K from Semen Impatientis in rat plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2017 Mar;31(3).

Animal Administration

Male Wistar rats (7 weeks old, 220±20 g, n=6) are fasted for 12 h. Total saponins of Semen Impatientis at a dose of 300 mg (in 10 mL)/kg are orally administered to rats using a gastric gavage tube. The doses of hosenkoside A is12.4 mg/kg for an oral dose of 300 mg/kg total saponins. Blood samples (0.20 mL) are collected from suborbital vein into heparinized tubes before administration (0 min), and 0.08, 0.25, 0.5, 0.75, 1, 1.5, 2, 4, 6, 8, 12 and 24 h after dosing.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献
  • [1]. Yu X, et al. An LC-MS/MS method for simultaneous determination of hosenkoside A and hosenkoside K from Semen Impatientis in rat plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2017 Mar;31(3).

Hosenkoside A

天然产物 糖类和糖苷 Saccharides and Glycosides

Hosenkoside A; 纯度: 99.38%

Hosenkoside A是从凤仙花种子中分离出的一种糖苷。

Hosenkoside A

Hosenkoside A Chemical Structure

CAS No. : 156791-82-1

规格 价格 是否有货 数量
5 mg ¥1900 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

Hosenkoside A 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Immunology/Inflammation Compound Library
  • Natural Product Library
  • Glycoside Compound Library

生物活性

Hosenkoside A is a baccharane glycoside isolated from the seeds of impatiens balsamina.

体内研究
(In Vivo)

The mean peak concentrations of hosenkoside A in rats after oral administration of total saponins of Semen Impatientis is 162.08±139.87 ng/mL, occurring at times of 0.67 h. The terminal half-lives of hosenkoside A is 5.39±2.06h[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

979.15

Formula

C48H82O20

CAS 号

156791-82-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

DMSO : 50 mg/mL (51.06 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.0213 mL 5.1065 mL 10.2129 mL
5 mM 0.2043 mL 1.0213 mL 2.0426 mL
10 mM 0.1021 mL 0.5106 mL 1.0213 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (2.55 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.55 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂:;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (2.55 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.55 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 3.

    请依序添加每种溶剂:;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.55 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.55 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献
  • [1]. Yu X, et al. An LC-MS/MS method for simultaneous determination of hosenkoside A and hosenkoside K from Semen Impatientis in rat plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2017 Mar;31(3).

Animal Administration

Male Wistar rats (7 weeks old, 220±20 g, n=6) are fasted for 12 h. Total saponins of Semen Impatientis at a dose of 300 mg (in 10 mL)/kg are orally administered to rats using a gastric gavage tube. The doses of hosenkoside A is12.4 mg/kg for an oral dose of 300 mg/kg total saponins. Blood samples (0.20 mL) are collected from suborbital vein into heparinized tubes before administration (0 min), and 0.08, 0.25, 0.5, 0.75, 1, 1.5, 2, 4, 6, 8, 12 and 24 h after dosing.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献
  • [1]. Yu X, et al. An LC-MS/MS method for simultaneous determination of hosenkoside A and hosenkoside K from Semen Impatientis in rat plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2017 Mar;31(3).

Hosenkoside C(Synonyms: 凤仙萜四醇苷C)

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Hosenkoside C (Synonyms: 凤仙萜四醇苷C)

Hosenkoside C 是从 Impatiens balsamina 种子中分离得到的一种 baccharane 糖苷。

Hosenkoside C(Synonyms: 凤仙萜四醇苷C)

Hosenkoside C Chemical Structure

CAS No. : 156764-83-9

规格 价格 是否有货
1 mg ¥1200 询问价格 & 货期
5 mg ¥3000 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

Hosenkoside C is a baccharane glycoside isolated from the seeds of Impatiens balsamina[1].

分子量

979.15

Formula

C48H82O20

CAS 号

156764-83-9

中文名称

凤仙萜四醇苷C

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Noboru Shoji, et al. Hosenkosides A, B, C, D, and E, novel baccharane glycosides from the seeds of Impatiens balsamina. Tetrahedron. 50, (17),1994 Apr:4973-4986.