荧光染料Dye Reagents HS-131;
HS-131 是一种近红外 Hsp90 的染料抑制剂,能够检测原癌基因驱动的乳腺癌,并能识别不同的人类乳腺癌分子亚型。

HS-131 Chemical Structure
CAS No. : 2084850-40-6
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生物活性 |
HS-131, a near infrared dye tethered Hsp90 inhibitor, is able to detect oncogene-driven breast cancers, including multiple different molecular subtypes of human breast cancers[1]. |
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体外研究 (In Vitro) |
Immunofluorescence[1]
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体内研究 (In Vivo) |
HS131 (10 nmol/mouse) could label breast cancers with different molecular subtypes, including MCF-7 and T-47D for luminal type, BT474M1 and KPL-4 for HER2+ subtype, MDA-MB-231 and MDA-MB-468 for triple negative subtype were chosen after considering the tumorigenic capacities of breast cancer cell lines in SCID mice[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
1318.68 |
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Formula |
C71H95N7O13S2 |
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CAS 号 |
2084850-40-6 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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