天然产物 天然产物苯丙素类 Phenylpropanoids
Desaminotyrosine (Synonyms: 对羟基苯丙酸; 3-(4-Hydroxyphenyl)propionic acid) 纯度: 99.81%
Desaminotyrosine 是一种微生物相关的代谢物,通过扩大 I 型干扰素 (type I interferon) 信号来阻止 influenza 的发生。
Desaminotyrosine Chemical Structure
CAS No. : 501-97-3
规格 | 价格 | 是否有货 | 数量 |
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Free Sample (0.1-0.5 mg) | Apply now | ||
10 mM * 1 mL in DMSO | ¥550 | In-stock | |
100 mg | ¥500 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
Desaminotyrosine 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Anti-Infection Compound Library
- Metabolism/Protease Compound Library
- Natural Product Library
- Antiviral Compound Library
- Human Endogenous Metabolite Compound Library
- Fragment Library
- Phenols Library
- Gut Microbial Metabolite Library
- Microbial Metabolite Library
- Food-Sourced Compound Library
生物活性 |
Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling. |
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IC50 & Target |
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体内研究 (In Vivo) |
Wild-type mice produce nanomoles of Desaminotyrosine per gram of feces and have picomolar quantities of Desaminotyrosine in the serum. Desaminotyrosine (200 mM) treatment before influenza infection, protects from influenza by type I interferon (IFN) signaling, with no effect on weight loss or survival in mice with or without vancomycin, neomycin, ampicillin, and metronidazole (VNAM). Desaminotyrosine enhances type I IFN in macrophages via type I IFN amplification in mice[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
166.18 |
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Formula |
C9H10O3 |
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CAS 号 |
501-97-3 |
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中文名称 |
根皮酸;对羟基苯丙酸 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (601.76 mM; Need ultrasonic) H2O : 33.33 mg/mL (200.57 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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Animal Administration [1] |
Mice[1] MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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参考文献 |
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