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Isoforskolin (Synonyms: Coleonol B)
Isoforskolin 是原产于中国的 C. forskohlii 的主要活性成分。在人单核白细胞中，Isoforskolin 减少了脂多糖 (LPS) 诱导的细胞因子如 TNF-α，IL-1β，IL-6 和 IL-8 的分泌。Isoforskolin 可作为抗炎剂，有潜力用于莱姆关节炎的研究。
Isoforskolin Chemical Structure
CAS No. : 64657-21-2
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥2290 | In-stock | |
| 5 mg | ￥6860 | In-stock | |
| 10 mg | 询价 | ||
| 50 mg | 询价 |
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Isoforskolin 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
| 生物活性 |
Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1]. |
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| IC50 & Target |
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| 体外研究 (In Vitro) |
Isoforskolin downregulates the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA)[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
410.50 |
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| Formula |
C22H34O7 |
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| CAS 号 |
64657-21-2 |
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| 中文名称 |
异佛司可林；异佛斯可林 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
-20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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| 参考文献 |
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