标签归档：janelia

Janelia Fluor® 549, SE(Synonyms: JF549, SE JF549, NHS)

发表于由

Janelia Fluor® 549, SE;(Synonyms: JF549, SE; JF549, NHS)

Janelia Fluor® 549, SE (JF549, SE) 是一种荧光染料，最大吸收波长 (λab (max)) 为 549 nm，最大发射波长 (λem (max)) 为 571 nm。Janelia Fluor® 产品根据美国专利获得许可，来自 Howard Hughes Medical Institute 的 No.9,933,417，10,018,624，10,161,932 和其他专利。

Janelia Fluor® 549, SEamp;;(Synonyms: JF549, SE; JF549, NHS)

Janelia Fluor® 549, SE Chemical Structure

CAS No. : 1811539-32-8

规格 是否有货
1 mg 询价

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生物活性

Janelia Fluor® 549, SE (JF549, SE) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm[1]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

分子量

551.55

Formula

C31H25N3O7
CAS 号

1811539-32-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jonathan B Grimm, et al. Synthesis of Janelia Fluor HaloTag and SNAP-Tag Ligands and Their Use in Cellular Imaging Experiments. Methods Mol Biol. 2017;1663:179-188.

Janelia Fluor® 549, Azide(Synonyms: JF549, Azide)

发表于由

Janelia Fluor® 549, Azide;(Synonyms: JF549, Azide)

Janelia Fluor® 549, Azide (JF549, Azide) 是一种荧光染料，最大吸收波长 (λab (max)) 为 549 nm，最大发射波长 (λem (max)) 为 571 nm。Janelia Fluor® 在美国专利下获得许可，来自 Howard Hughes Medical Institute 的 No.9,933,417，10,018,624，10,161,932 和其他专利。

Janelia Fluor® 549, Azideamp;;(Synonyms: JF549, Azide)

Janelia Fluor® 549, Azide Chemical Structure

规格 是否有货
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500 mg ; 询价 ;

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生物活性

Janelia Fluor® 549, Azide (JF549, Azide) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm[1]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

分子量

654.71

Formula

C35H38N6O7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jonathan B Grimm, et al. Synthesis of Janelia Fluor HaloTag and SNAP-Tag Ligands and Their Use in Cellular Imaging Experiments. Methods Mol Biol. 2017;1663:179-188.

Janelia Fluor® 549 TFA(Synonyms: JF549 TFA)

发表于由

Janelia Fluor® 549 TFA;(Synonyms: JF549 TFA)

Janelia Fluor® 549 TFA (JF549 TFA) 是一种荧光染料，最大吸收波长 (λab (max)) 为 549 nm，最大发射波长 (λem (max)) 为 571 nm。Janelia Fluor® 产品根据美国专利获得许可，来自 Howard Hughes Medical Institute 的 No.9,933,417，10,018,624，10,161,932 和其他专利。

Janelia Fluor® 549 TFAamp;;(Synonyms: JF549 TFA)

Janelia Fluor® 549 TFA Chemical Structure

CAS No. : 2245946-45-4

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Janelia Fluor® 549 TFA (JF549 TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm[1]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

分子量

568.50

Formula

C29H23F3N2O7
CAS 号

2245946-45-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jonathan B Grimm, et al. Synthesis of Janelia Fluor HaloTag and SNAP-Tag Ligands and Their Use in Cellular Imaging Experiments. Methods Mol Biol. 2017;1663:179-188.

Janelia Fluor® 549, Maleimide TFA(Synonyms: JF549, Maleimide TFA)

发表于由

Janelia Fluor® 549, Maleimide TFA;(Synonyms: JF549, Maleimide TFA)

Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) 是一种荧光染料，最大吸收波长 (λab (max)) 为 549 nm，最大发射波长 (λem (max)) 为 571 nm。Janelia Fluor® 产品在美国专利下获得许可，来自 Howard Hughes Medical Institute 的 No.9,933,417，10,018,624，10,161,932 和其他专利。

Janelia Fluor® 549, Maleimide TFAamp;;(Synonyms: JF549, Maleimide TFA)

Janelia Fluor® 549, Maleimide TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm[1]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

分子量

690.62

Formula

C35H29F3N4O8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jonathan B Grimm, et al. Synthesis of Janelia Fluor HaloTag and SNAP-Tag Ligands and Their Use in Cellular Imaging Experiments. Methods Mol Biol. 2017;1663:179-188.

Janelia Fluor® 585, SE(Synonyms: JF585, SE JF585, NHS)

发表于由

Janelia Fluor® 585, SE;(Synonyms: JF585, SE; JF585, NHS)

Janelia Fluor® 585, SE (JF585, SE) 是一种橙色荧光染料，含有 NHS 酯，能与伯胺基共轭。Janelia Fluor® 585, SE 可用于结构光照明 (SIM) 和受激发射损耗荧光显微技术(STED)，还可转化为光活化衍生物用于单分子定位显微镜 (SMLM) 实验。Janelia Fluor® 产品在美国专利下获得许可，来自 Howard Hughes Medical Institute 的 No.9,933,417，10,018,624，10,161,932 和其他专利。

Janelia Fluor® 585, SEamp;;(Synonyms: JF585, SE; JF585, NHS)

Janelia Fluor® 585, SE Chemical Structure

CAS No. : 1811539-88-4

规格 是否有货
1 mg 询价

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生物活性

Janelia Fluor® 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor® 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments[1]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

体外研究
(In Vitro)

Maximum absorption wavelength (λabs)=585 nm, maximum emission wavelength (λem)=609 nm[1].
The JF585-SNAP-tag ligand (24) also functioned as a cellular label. The new HaloTag ligands derived from JF585 and JF635 show a high degree of chromogenicity and fluorogenicity, a critical parameter in advanced imaging experiments[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

649.59

Formula

C34H27F4N3O6
CAS 号

1811539-88-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Grimm JB, Muthusamy AK, Liang Y, et al. A general method to fine-tune fluorophores for live-cell and in vivo imaging. Nat Methods. 2017;14(10):987-994. doi:10.1038/nmeth.4403

Janelia Fluor® 646, Tetrazine(Synonyms: JF646, Tetrazine)

发表于由

Janelia Fluor® 646, Tetrazine;(Synonyms: JF646, Tetrazine)

Janelia Fluor® 646, Tetrazine (JF646, Tetrazine)，一种红色荧光染料包含tetrazine 基团。JF646, Tetrazine 可用于细胞成像实验中。Janelia Fluor® 产品在美国专利下获得许可，来自 Howard Hughes Medical Institute 的 No.9,933,417，10,018,624，10,161,932 和其他专利。

Janelia Fluor® 646, Tetrazineamp;;(Synonyms: JF646, Tetrazine)

Janelia Fluor® 646, Tetrazine Chemical Structure

CAS No. : 2042192-00-5

规格 是否有货
100 μg 询价

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生物活性

Janelia Fluor® 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging[1]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

体外研究
(In Vitro)

Excitation maximum=646 nm; emission maximum=664 nm[1].
JF646 can serve as ligand for self-labeling tag (such as HaloTag) [1].
JF646, Tetrazine is modified by JF646. JF646, a red fluorescent dye, is photostable, membrane-permeable, has a high extinction coefficient[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

665.82

Formula

C38H35N7O3Si
CAS 号

2042192-00-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Grimm JB, et al. A general method to improve fluorophores for live-cell and single-molecule microscopy. Nat Methods. 2015;12(3):244-250. doi:10.1038/nmeth.3256

    [2]. Basu S, et al. FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells. Nat Commun. 2018;9(1):2520. Published 2018 Jun 28.

Janelia Fluor® 646, Azide(Synonyms: JF646, Azide)

发表于由

Janelia Fluor® 646, Azide;(Synonyms: JF646, Azide)

Janelia Fluor® 646, Azide (JF646, Azide) 是一种红色荧光染料，含有 click chemistry 基团叠氮化物。Janelia Fluor® 646, Azide 可用于活细胞成像实验中。Janelia Fluor® 产品在美国专利下获得许可，来自 Howard Hughes Medical Institute 的 No.9,933,417，10,018,624，10,161,932 和其他专利。

Janelia Fluor® 646, Azideamp;;(Synonyms: JF646, Azide)

Janelia Fluor® 646, Azide Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Janelia Fluor® 646, Azide (JF646, Azide) is a red fluorogenic fluorescent dye containing a click chemistry group Azide. Janelia Fluor® 646, Azide can be used for live-cell imaging experiments[1][2]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

体外研究
(In Vitro)

Maximum absorption wavelength (λabs)= 646 nm, maximum emission wavelength (λem)=664 nm[1].
JF646 can serve as a ligand for self-labeling tag (such as HaloTag)[1].
Janelia Fluor® 646, Azide is modified by JF646. JF646, a red fluorescent dye, is photostable, membrane-permeable, has a high extinction coefficient[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

696.87

Formula

C37H44N6O6Si
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Grimm JB, Muthusamy AK, Liang Y, et al. A general method to fine-tune fluorophores for live-cell and in vivo imaging. Nat Methods. 2017;14(10):987-994. doi:10.1038/nmeth.4403.

    [2]. Basu S, et al. FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells. Nat Commun. 2018;9(1):2520. Published 2018 Jun 28.

Janelia Fluor® 646 TFA(Synonyms: JF646 TFA)

发表于由

Janelia Fluor® 646 TFA;(Synonyms: JF646 TFA)

Janelia Fluor® 646 TFA (JF646 TFA) 是一种红色荧光染料，可用于 Janelia Fluor 646 HaloTag 和 SNAP-Tag 配体的合成。Janelia Fluor® 646 TFA 可用于活体细胞成像实验中。Janelia Fluor® 产品在美国专利下获得许可，来自 Howard Hughes Medical Institute 的 No.9,933,417，10,018,624，10,161,932 和其他专利。

Janelia Fluor® 646 TFAamp;;(Synonyms: JF646 TFA)

Janelia Fluor® 646 TFA Chemical Structure

规格 是否有货
1 mg 询价
5 mg 询价

* Please select Quantity before adding items.

生物活性

Janelia Fluor® 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments[1][2]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

体外研究
(In Vitro)

JF646 TFA: λmax (nm)=646, λem (nm) =664[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

610.65

Formula

C31H29F3N2O6Si
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Grimm JB, Muthusamy AK, Liang Y, et al. A general method to fine-tune fluorophores for live-cell and in vivo imaging. Nat Methods. 2017;14(10):987-994. doi:10.1038/nmeth.4403.

荧光染料Janelia Fluor® 526, SE(Synonyms: JF526, SE; JF526, NHS)

发表于由

荧光染料Dye Reagents Janelia Fluor® 526, SE;(Synonyms: JF526, SE; JF526, NHS)

Janelia Fluor® 526, SE (JF526,SE) 是一种含有 NHS 酯基的荧光黄色荧光染料。JF526 是一种用于荧光配体的多功能支架，包括用于遗传编码的自标记蛋白质标签和用于内源性结构的染色。Janelia Fluor® 产品在美国专利下获得许可，来自 Howard Hughes Medical Institute 的 No.9,933,417，10,018,624，10,161,932 和其他专利。

Janelia Fluor® 526, SE(Synonyms: JF526, SE; JF526, NHS)

Janelia Fluor® 526, SE Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Janelia Fluor® 526, SE (JF526,SE) is a fluorogenic yellow fluorescent dye that contains NHS ester group. JF526 is a versatile scaffold for fluorogenic ligands, including labels for genetically encoded self-labeling protein tags and stains for endogenous structures[1]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

体外研究
(In Vitro)

Excitation maximum=526 nm; emission maximum=550 nm[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

659.49

Formula

C31H19F6N3O7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zheng Q, et al. Rational Design of Fluorogenic and Spontaneously Blinking Labels for Super-Resolution Imaging [published correction appears in ACS Cent Sci. 2020 Oct 28;6(10):1844]. ACS Cent Sci. 2019;5(9):1602-1613.

荧光染料Janelia Fluor® 669, SE(Synonyms: JF669, SE; JF669, NHS)

发表于由

荧光染料Dye Reagents Janelia Fluor® 669, SE;(Synonyms: JF669, SE; JF669, NHS)

Janelia Fluor® 669, SE (JF669, SE) 是一种红色的荧光染料，可与含巯基的卤代标记配体在温和的条件下 (DIEA, DMF) 反应，一步形成 JF669-HaloTag (Ex = 669 nm; Em = 682 nm)。Janelia Fluor® 产品在美国专利下获得许可，来自 Howard Hughes Medical Institute 的 No.9,933,417，10,018,624，10,161,932 和其他专利。

Janelia Fluor® 669, SE(Synonyms: JF669, SE; JF669, NHS)

Janelia Fluor® 669, SE Chemical Structure

CAS No. : 2127150-20-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Janelia Fluor® 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669−HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm)[1]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

体外研究
(In Vitro)

JF669 undergoes rapid conversion to thioether product (<5 min to completion) in organic solvents, where the dye predominantly adopts closed form[1].
JF669 displays comparatively excellent photostability, retaining 97% fluorescence after the same number of cycles[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

693.76

Formula

C34H30F3N3O6SSi
CAS 号

2127150-20-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jonathan B Grimm, et al. General Synthetic Method for Si-Fluoresceins and Si-Rhodamines. ACS Cent Sci. 2017 Sep 27;3(9):975-985.