标签归档：leesggglvqpggsmk

LEESGGGLVQPGGSMK acetate

发表于由

LEESGGGLVQPGGSMK acetate; 纯度: 99.01%

LEESGGGLVQPGGSMK acetate，一种蛋白水解肽，是 Infliximab 的一种成分，可用于 Infliximab 的定量分析。Infliximab 是一种与 TNF-α 特异性结合的嵌合单克隆 IgG1 抗体。

LEESGGGLVQPGGSMK acetateamp;;

LEESGGGLVQPGGSMK acetate Chemical Structure

规格 价格 是否有货 数量
5 mg ￥3500 In-stock
10 mg ￥6100 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

LEESGGGLVQPGGSMK acetate 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

LEESGGGLVQPGGSMK acetate, a proteolysis peptide, is a component of Infliximab. LEESGGGLVQPGGSMK acetate can be used for quantitative analysis of Infliximab. Infliximab is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α[1].

体外研究
(In Vitro)

The anti-TNF antibodies blocking the action of TNF alpha revolutionized therapy of TNF-related diseases such as Inflammatory Bowel Disease, lupus, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis. By neutralizing TNF activity, anti-TNF antibodies promote mucosal healing and induce long-term remissions in vivo. The main anti-TNF antibodies that are currently authorized encompass Infliximab, Etanercept, Adalimumab, Certolizumab and Golimumab[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1605.76

Formula

C66H112N18O26S
Sequence Shortening

LEESGGGLVQPGGSMK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : 100 mg/mL (62.28 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.6228 mL 3.1138 mL 6.2276 mL
5 mM 0.1246 mL 0.6228 mL 1.2455 mL
10 mM 0.0623 mL 0.3114 mL 0.6228 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Dorothée LEBERT, et al. A method for quantifying therapeutic antibodies. EP3371592A1.

LEESGGGLVQPGGSMK

发表于由

LEESGGGLVQPGGSMK;

LEESGGGLVQPGGSMK，一种蛋白水解肽，是 Infliximab 的一种成分，可用于 Infliximab 的定量分析。Infliximab 是一种与 TNF-α 特异性结合的嵌合单克隆 IgG1 抗体。

LEESGGGLVQPGGSMKamp;;

LEESGGGLVQPGGSMK Chemical Structure

CAS No. : 2096980-79-7

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

LEESGGGLVQPGGSMK 的其他形式现货产品:

LEESGGGLVQPGGSMK acetate

生物活性

LEESGGGLVQPGGSMK, a proteolysis peptide, is a component of Infliximab. LEESGGGLVQPGGSMK can be used for quantitative analysis of Infliximab. Infliximab is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α[1].

体外研究
(In Vitro)

The anti-TNF antibodies blocking the action of TNF alpha revolutionized therapy of TNF-related diseases such as Inflammatory Bowel Disease, lupus, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis. By neutralizing TNF activity, anti-TNF antibodies promote mucosal healing and induce long-term remissions in vivo. The main anti-TNF antibodies that are currently authorized encompass Infliximab, Etanercept, Adalimumab, Certolizumab and Golimumab[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1545.71

Formula

C64H108N18O24S
CAS 号

2096980-79-7
Sequence

Leu-Glu-Glu-Ser-Gly-Gly-Gly-Leu-Val-Gln-Pro-Gly-Gly-Ser-Met-Lys
Sequence Shortening

LEESGGGLVQPGGSMK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Dorothée LEBERT, et al. A method for quantifying therapeutic antibodies. EP3371592A1.

LEESGGGLVQPGGSMK TFA

发表于由

LEESGGGLVQPGGSMK TFA;

LEESGGGLVQPGGSMK TFA，一种蛋白水解肽，是 Infliximab 的一种成分，可用于 Infliximab 的定量分析。Infliximab 是一种与 TNF-α 特异性结合的嵌合单克隆 IgG1 抗体。

LEESGGGLVQPGGSMK TFAamp;;

LEESGGGLVQPGGSMK TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

LEESGGGLVQPGGSMK TFA 的其他形式现货产品:

LEESGGGLVQPGGSMK acetate

生物活性

LEESGGGLVQPGGSMK TFA, a proteolysis peptide, is a component of Infliximab. LEESGGGLVQPGGSMK TFA can be used for quantitative analysis of Infliximab. Infliximab is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α[1].

体外研究
(In Vitro)

The anti-TNF antibodies blocking the action of TNF alpha revolutionized therapy of TNF-related diseases such as Inflammatory Bowel Disease, lupus, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis. By neutralizing TNF activity, anti-TNF antibodies promote mucosal healing and induce long-term remissions in vivo. The main anti-TNF antibodies that are currently authorized encompass Infliximab, Etanercept, Adalimumab, Certolizumab and Golimumab[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1659.73

Formula

C66H109F3N18O26S
Sequence Shortening

LEESGGGLVQPGGSMK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Dorothée LEBERT, et al. A method for quantifying therapeutic antibodies. EP3371592A1.