标签归档：leu

[Ala11,D-Leu15]-Orexin B(human) TFA

发表于由

[Ala11,D-Leu15]-Orexin B(human) TFA;

[Ala11,D-Leu15]-Orexin B(human) TFA 是一种有效的，选择性的 orexin-2 receptor (OX2) 的激动剂。[Ala11,D-Leu15]-Orexin B(human) TFA 对 OX2 (EC50=0.13 nM) 比对 OX1 (52 nM) 高出 400 倍的选择性。

[Ala11,D-Leu15]-Orexin B(human) TFAamp;;

[Ala11,D-Leu15]-Orexin B(human) TFA Chemical Structure

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生物活性

[Ala11,D-Leu15]-Orexin B(human) TFA is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) TFA shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (52 nM)[1].

IC50 Target[1]

OX2

0.13 (EC50)

OX1

52 (EC50)

分子量

2971.28

Formula

C122H207F3N44O37S
Sequence

Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Ala-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Sequence Shortening

RSGPPGLQGRAQRLLQASGNHAAGILTM-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Asahi S, et al. Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B. Bioorg Med Chem Lett. 2003;13(1):111-113.

H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH

发表于由

H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH;

H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH (EM7) 是间充质干细胞(MSC)特异性肽。

H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OHamp;;

H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH Chemical Structure

CAS No. : 683750-83-6

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生物活性

H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH (EM7) is a mesenchymal stem cells (MSC)-specific peptide[1].

分子量

858.06

Formula

C38H67N9O11S
CAS 号

683750-83-6
Sequence Shortening

EPLQLKM
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Limin Cao, et al. The interplay of T1- and T2-relaxation on T1-weighted MRI of hMSCs induced by Gd-DOTA-peptides. Biomaterials. 2014 Apr;35(13):4168-74.

[Leu31,Pro34]-Neuropeptide Y (porcine)

发表于由

[Leu31,Pro34]-Neuropeptide Y (porcine); 纯度: 98.66%

[Leu31,Pro34]- Neuropeptide Y (porcine) 是一种神经肽 Y (NPY) 类似物，是一种选择性的 NPY Y1 受体激动剂。[Leu31,Pro34]- Neuropeptide Y (porcine) 表现出抗焦虑作用。

[Leu31,Pro34]-Neuropeptide Y (porcine)amp;;

[Leu31,Pro34]-Neuropeptide Y (porcine) Chemical Structure

CAS No. : 125580-28-1

规格 价格 是否有货 数量
1 mg ￥1300 In-stock
5 mg ￥3900 In-stock
10 mg ￥6200 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

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[Leu31,Pro34]-Neuropeptide Y (porcine) 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

[Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects[1][2].

IC50 Target[1]

NPY Y1 receptor

;

体内研究
(In Vivo)

[Leu31,Pro34]-Neuropeptide Y (porcine) displaces radiolabeled NPY from cells that express Y1 receptors in a series of human neuroblastoma cell lines and on rat PC-12 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

4222.63

Formula

C190H286N54O56
CAS 号

125580-28-1
Sequence Shortening

YPSKPDNPGEDAPAEDLARYYSALRHYINLLTRPRY-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : ≥ 100 mg/mL (23.68 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.2368 mL 1.1841 mL 2.3682 mL
5 mM 0.0474 mL 0.2368 mL 0.4736 mL
10 mM 0.0237 mL 0.1184 mL 0.2368 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Fuhlendorff J, et, al. [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist. Proc Natl Acad Sci U S A. 1990 Jan;87(1):182-6.

    [2]. Kokare DM, et, al. Interaction between neuropeptide Y and alpha-melanocyte stimulating hormone in amygdala regulates anxiety in rats. Brain Res. 2005 May 10;1043(1-2):107-14.

D[LEU4,LYS8]-VP

发表于由

D[LEU4,LYS8]-VP;

D[LEU4,LYS8]-VP 是血管加压素 V1b 受体的选择性激动剂，对大鼠，人类和小鼠 V1b 受体的 Ki 值分别为 0.16 nM，0.52 nM 和 1.38 nM。D[LEU4,LYS8]-VP 具有较弱的抗利尿剂、升压药和体外催产素活性。

D[LEU4,LYS8]-VPamp;;

D[LEU4,LYS8]-VP Chemical Structure

CAS No. : 42061-33-6

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D[LEU4,LYS8]-VP 的其他形式现货产品:

D[LEU4,LYS8]-VP TFA

生物活性

D[LEU4,LYS8]-VP is a selective agonist of vasopressin V1b receptor, with the Kis of 0.16 nM, 0.52 nM, and 0.1.38 nM for rat, human and mouse V1b receptor, respectively. D[LEU4,LYS8]-VP has weak antidiuretic, vasopressor, and in vitro oxytocic activities[1][2].

IC50 Target

vasopressin V1b receptor[1]
分子量

1026.23

Formula

C47H67N11O11S2
CAS 号

42061-33-6
Sequence

{Mpa}-Tyr-Phe-Leu-Asn-Cys-Pro-Lys-Gly (Disulfide bridge:Mpa1-Cys6)
Sequence Shortening

{Mpa}-YFLNCPKG-NH2 (Disulfide bridge:Mpa1-Cys6)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Ana P, et, al. Pharmacological and physiological characterization of d[Leu4, Lys8]vasopressin, the first V1b-selective agonist for rat vasopressin/oxytocin receptors. Endocrinology. 2007 Sep; 148(9): 4136-46.

    [2]. Ana P, et, al. Design and synthesis of the first selective agonists for the rat vasopressin V(1b) receptor: based on modifications of deamino-[Cys1]arginine vasopressin at positions 4 and 8. J Med Chem. 2007 Feb 22; 50(4): 835-47.

[Leu31,Pro34]-Neuropeptide Y(human,rat)

发表于由

[Leu31,Pro34]-Neuropeptide Y(human,rat);

[Leu31,Pro34]-Neuropeptide Y(human,rat) 是一种特定的神经肽 Y Y1 受体激动剂。[Leu31,Pro34]-Neuropeptide Y(human,rat) 也激活 Y4，Y5。[Leu31,Pro34]-Neuropeptide Y(human,rat) 可以增加麻醉大鼠的血压，也增加饮食摄入量。

[Leu31,Pro34]-Neuropeptide Y(human,rat)amp;;

[Leu31,Pro34]-Neuropeptide Y(human,rat) Chemical Structure

CAS No. : 132699-73-1

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[Leu31,Pro34]-Neuropeptide Y(human,rat) 的其他形式现货产品:

[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA

生物活性

[Leu31,Pro34]-Neuropeptide Y(human,rat) is a specific neuropeptide Y Y1 receptor agonist. [Leu31,Pro34]-Neuropeptide Y(human,rat) slao activates Y4, Y5. [Leu31,Pro34]-Neuropeptide Y(human,rat) can increase blood pressure in anesthetized rats and increases food intake[1][2].

IC50 Target[1][2]

NPY Y1 receptor

;

NPY Y4 receptor

;

NPY Y5 receptor

;

体外研究
(In Vitro)

[Leu31,Pro34]-Neuropeptide Y(human,rat) has Ki values of 0.39 nM, 0.499 nM, 0.31 nM for Y1, Y4, Y5 in HEK cell lines. [Leu31,Pro34]-Neuropeptide Y(human,rat) has a Ki of >1000 for Y2 in HEK cell lines[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

[Leu31,Pro34]-Neuropeptide Y(human,rat) (30 pmol; microinjected into paraventricular nucleus) increases food intake in the rats (350±400 g)[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

4240.73

Formula

C189H284N54O56S
CAS 号

132699-73-1
Sequence

Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
Sequence Shortening

YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. J Fuhlendorff, et al. [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist. Proc Natl Acad Sci U S A. 1990 Jan;87(1):182-6.

    [2]. K McCrea, et al. 2-36[K4,RYYSA(19-23)]PP a novel Y5-receptor preferring ligand with strong stimulatory effect on food intake. Regul Pept. 2000 Feb 8;87(1-3):47-58.

    [3]. A Kask, et al. Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y1-selective antagonist BIBP3226. Br J Pharmacol. 1998 Aug;124(7):1507-15.

[Ala11,D-Leu15]-Orexin B(human)

发表于由

[Ala11,D-Leu15]-Orexin B(human);

[Ala11,D-Leu15]-Orexin B(human) 是一种有效的，选择性的 orexin-2 receptor (OX2) 的激动剂。[Ala11,D-Leu15]-Orexin B(human) 对 OX2 (EC50=0.13 nM) 比对 OX1 (52 nM) 高出 400 倍的选择性。

[Ala11,D-Leu15]-Orexin B(human)amp;;

[Ala11,D-Leu15]-Orexin B(human) Chemical Structure

CAS No. : 532932-99-3

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生物活性

[Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (52 nM)[1].

IC50 Target[1]

OX2

0.13 nM (EC50)

OX1

52 nM (EC50)

分子量

2857.26

Formula

C120H206N44O35S
CAS 号

532932-99-3
Sequence

Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Ala-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Sequence Shortening

RSGPPGLQGRAQRLLQASGNHAAGILTM-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Asahi S, et al. Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B. Bioorg Med Chem Lett. 2003;13(1):111-113.

Tyrosylleucine(Synonyms: Tyr-Leu)

发表于由

Tyrosylleucine;(Synonyms: Tyr-Leu)

Tyrosylleucine (Tyr-Leu, YL) 是具有口服活性的二肽，具有类似抗抑郁活性。

Tyrosylleucineamp;;(Synonyms: Tyr-Leu)

Tyrosylleucine Chemical Structure

CAS No. : 17355-10-1

规格 是否有货
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Tyrosylleucine 的其他形式现货产品:

Tyrosylleucine TFA

生物活性

Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity[1].

体内研究
(In Vivo)

Tyrosylleucine (YL), administered orally, intracerebroventricularly, or intraperitoneally exhibits a potent antidepressant-like activity in the forced swim and tail suspension tests in naïve mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male ddY mice (24-27 g)[1]
Dosage: 0.1-30 mg/kg, i.p.; 0.1-1.0 nmol/mouse, i.c.v.; 30-100 mg/kg, p.o.
Administration: Administered orally, intracerebroventricularly, or intraperitoneally
Result: Decreased immobility time after intraperitoneal (1-30 mg/kg) and intracerebroventricular (0.3-1 nmol/mouse) administrations in the FST.
Exhibited a potent antidepressant-like activity in the forced swim and tail suspension tests in naïve mice.

分子量

294.35

Formula

C15H22N2O4
CAS 号

17355-10-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
溶解性数据
In Vitro:;

H2O : 250 mg/mL (849.33 mM; Need ultrasonic)

DMSO : 250 mg/mL (849.33 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.3973 mL 16.9866 mL 33.9732 mL
5 mM 0.6795 mL 3.3973 mL 6.7946 mL
10 mM 0.3397 mL 1.6987 mL 3.3973 mL

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂：;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.08 mg/mL (7.07 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (7.07 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂：;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (7.07 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (7.07 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
  • 3.

    请依序添加每种溶剂：;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.08 mg/mL (7.07 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (7.07 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献

  • [1]. Takafumi Mizushige, et al. Dipeptide tyrosyl-leucine exhibits antidepressant-like activity in mice. Sci Rep. 2020 Feb 10;10(1):2257.

    [2]. Norimasa Kanegawa, et al. Dipeptide Tyr-Leu (YL) exhibits anxiolytic-like activity after oral administration via activating serotonin 5-HT1A, dopamine D1 and GABAA receptors in mice. FEBS Lett. 2010 Feb 5;584(3):599-604.

[Leu3]-Oxytocin

发表于由

[Leu3]-Oxytocin;

[Leu3]-Oxytocin，一种催产素类似物，由序列位置3的结构变化衍生而来，被亮氨酸 (Leu) 取代。

[Leu3]-Oxytocinamp;;

[Leu3]-Oxytocin Chemical Structure

CAS No. : 4294-11-5

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

[Leu3]-Oxytocin, an oxytocin analogue, is derived by structural variation in sequence position 3 replaced by leucine (Leu)[1].

分子量

1007.19

Formula

C43H66N12O12S2
CAS 号

4294-11-5
Sequence Shortening

CYLQNCPLG-NH2 (Disulfide bridge:Cys1-Cys6)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Krejcí I, et al. Effect of magnesium on the action of oxytocin and a group of analogues on the uterus in vitro. Eur J Pharmacol. 1968;2(5):393-398.

Fmoc-Leu-Thr(psi(Me,Me)pro)-OH

发表于由

Fmoc-Leu-Thr(psi(Me,Me)pro)-OH;

Fmoc-Leu-Thr(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Leu-Thr(psi(Me,Me)pro)-OHamp;;

Fmoc-Leu-Thr(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 955048-89-2

规格 是否有货
100 mg ; 询价 ;
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生物活性

Fmoc-Leu-Thr(psi(Me,Me)pro)-OH is a dipeptide.

分子量

494.58

Formula

C28H34N2O6
CAS 号

955048-89-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA(Synonyms: For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA)

发表于由

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA;(Synonyms: For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA)

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) 是一种甲酰肽受体 (FPR) 激动剂。

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFAamp;;(Synonyms: For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA)

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA 的其他形式现货产品:

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys

生物活性

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist[1].

IC50 Target

Formyl peptide receptor[1]
分子量

938.04

Formula

C45H66F3N7O11
Sequence

N-Formyl-{NLE}-Leu-Phe-{NLE}-Tyr-Lys
Sequence Shortening

N-Formyl-{NLE}-LF-{NLE}-YK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Stenfeldt AL, et al. The non-steroidal anti-inflammatory drug piroxicam blocks ligand binding to the formyl peptidereceptor but not the formyl peptide receptor like 1. Biochem Pharmacol. 2007 Oct 1;74(7):1050-6.