NGR peptide Trifluoroacetate;(Synonyms: NGR肽三氟乙酸盐) 纯度: ge;98.0%
NGR peptide Trifluoroacetate 是含有天冬酰胺-甘氨酸-精氨酸 (NGR) 基序的肽,NGR peptide (NGR 肽) 可靶向肿瘤新生血管上皮细胞特异过量表达的 CD13 受体。
NGR peptide Trifluoroacetate Chemical Structure
规格 | 价格 | 是否有货 | 数量 |
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10;mM;*;1 mL in Water | ¥4770 | In-stock | |
1 mg | ¥1000 | In-stock | |
5 mg | ¥3000 | In-stock | |
10 mg | ; | 询价 | ; |
50 mg | ; | 询价 | ; |
* Please select Quantity before adding items.
NGR peptide Trifluoroacetate 相关产品
bull;相关化合物库:
- Covalent Screening Library Plus
- Bioactive Compound Library Plus
- Metabolism/Protease Compound Library
- Anti-Cancer Compound Library
- Covalent Screening Library
- Targeted Diversity Library
- Peptide Library
生物活性 |
NGR peptide Trifluoroacetate containing the asparagine-glycine-arginine (NGR) motif is recognized by CD13/aminopeptidase N (APN) receptor isoforms that are selectively overexpressed in tumor neovasculature. |
IC50 Target |
CD13/aminopeptidase N (APN) receptor[1] |
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体外研究 (In Vitro) |
NGR peptide can selectively bind to APN/CD13 either immune-captured or expressed on the surface of cells, the receptor of the tumor-homing NGR peptide was suspected to be APN/CD13. The NGR peptide is reported to have the greatest tumor selectivity. An anti-cancer drug Doxorubicin (DOX) coupled to an NGR peptide displays enhanced anti-tumor effects with even lower toxicity than the free drug itself[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
NGR peptide imaging in vivo not only provides more insight into NGR’s targeting process, including bio-distribution and pharmacokinetics, but also reveals angiogenic activities related to tumor progression and malignancy[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
722.72 |
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Formula |
C22H37F3N10O10S2 |
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Sequence |
Cys-Asn-Gly-Arg-Cys-Gly |
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Sequence Shortening |
CNGRCG |
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中文名称 |
NGR肽三氟乙酸盐 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Sealed storage, away from moisture
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture) |
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溶解性数据 |
In Vitro:;
H2O : 50 mg/mL (69.18 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
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参考文献 |
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