标签归档：nir

NIR-H2O2

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NIR-H2O2;

NIR-H2O2 是一种可透过细胞的 NIR 荧光启动传感器。NIR-H2O2 在 NIR 区域内同时具有吸收和发射作用。当在 NIR 区域激发时，NIR-H2O2 对 H2O2 产生较大的启动 NIR 荧光信号。NIR-H2O2 能够对活细胞和小鼠中内源性产生的 H2O2 进行成像。

NIR-H2O2amp;;

NIR-H2O2 Chemical Structure

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生物活性

NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H2O2 in living cells and mice[1].

体外研究
(In Vitro)

NIR-H2O2 is highly selective to H2O2 over other typical ROS and biorelevant species[1].
HeLa cells incubated with NIR-H2O2 (5 μM) for 30 min at 37 °C provide almost no fluorescence. However, when the living HeLa cells loaded with NIR-H2O2 are further treated with H2O2, they give strong fluorescence. NIR-H2O2 is cell membrane permeable and responsive to H2O2 in the living cells. When stimulated by phorbol myristate acetate (PMA), macrophage cells may produce endogenous H2O2. The living RAW264.7 macrophage cells loaded with only the NIR sensor NIR-H2O2 (1 μM) display almost no fluorescence. However, the macrophage cells coincubated with PMA (3.0 μg/mL) and the sensor NIR-H2O2 (1 μM) exhibit a dramatic enhancement in the red emission. NIR-H2O2 is capable of fluorescent imaging of endogenously produced H2O2 in the living RAW264.7 macrophage cells. The mitochondria staining experiments suggest that the sensor mainly associates with the mitochondria of RAW264.7 macrophage cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

The H2O2 production in vivo was generated by activated macrophages and neutrophils in a lipopolysaccharide (LPS) model of acute inflammation. The mice treated with both LPS and NIR-H2O2 exhibit a significantly higher fluorescence readout than the mice untreated or treated with only NIR-H2O2. The mice loaded with LPS and NIR-H2O2 have approximately 10- and 20-fold higher fluorescence intensity than the mice loaded with saline and the sensor and the mice loaded with saline, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

565.89

Formula

C34H33BClNO4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Yuan L, et al. A unique approach to development of near-infrared fluorescent sensors for in vivo imaging. J Am Chem Soc. 2012 Aug 15;134(32):13510-23.

Sartorius赛多利斯NIR 过程测定仪 PMD500 (实验室版本)

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Sartorius赛多利斯NIR 过程测定仪 PMD500 (实验室版本)

Sartorius赛多利斯 PMD500NIR 过程测定仪

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Sartorius赛多利斯NIR 过程测定仪 PMD500 (实验室版本)

这些模块过程分析仪能够在您的实验室中准确进行液体，糊状物和固体物质的非接触水份和多组分分析。 除了传统测量浓度的方法，PMD500还具有完整控制和产品分类的程序功能。合并后的NIR 和 UV/V 的光谱仪和可选用的高分辨率的数码相机得到广泛的测量结果，其中包括，产品的视觉特征。一系列全面的工具能够把您的日常实验室工作灵活的集成一体。
 
  • 过程监测和控制
  • 在线水份分析
  • 多参数测量浓度
  • 均匀性测量
  • 检查混合完整性
  • 样品鉴定
  • 混合物的纯净度测试
  • 监测可视特征
 
  • 过程监测和控制
  • 在线水份分析
  • 多参数测量浓度
  • 均匀性测量
  • 检查混合完整性
  • 样品鉴定
  • 混合物的纯净度测试
  • 监测可视特征
 
  • 过程监测和控制
  • 在线水份分析
  • 多参数测量浓度
  • 均匀性测量
  • 检查混合完整性
  • 样品鉴定
  • 混合物的纯净度测试
  • 监测可视特征

赛多利斯

Sartorius赛多利斯NIR 过程分析仪器 PMD500

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Sartorius赛多利斯NIR 过程分析仪器 PMD500

Sartorius赛多利斯PMD500NIR过程分析仪器

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Sartorius赛多利斯NIR 过程分析仪器 PMD500

这些超现代的，高科技光学测量器结合一个高分辨率的数字镜头和一个全面的软件包，使UV|VIS和 NIR 光谱的排列具有唯一和灵活 。成分的浓度，例如水，湿度，脂肪，蛋白质，溶剂等等，可以精确的测量用在线测量法。UV|VIS 和 NIR 的结合是分光计和可选的可用高分辨率数字镜头的产物，全面的测量法包括，其中之一，可是的产品特点。一个全面的工具能够使联合工艺灵活，例如在搅拌器中，料罐中或者管道系统中。
 
  • 在线水份分析
  • 过程监测和控制
  • 多参数测量浓度
  • 均匀性测量
  • 检查混合完整性
  • 样品鉴定
  • 混合物的纯净度测试
  • 用来监测可视特征
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荧光染料AgAuSe QDs(Synonyms: AgAuSe)

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荧光染料Dye Reagents AgAuSe QDs;(Synonyms: AgAuSe)

AgAuSe QDs (AgAuSe) 是一种近红外 (NIR) 荧光量子点 (QDs)，在 820-1170 nm 范围内发出明亮的光。AgAuSe QDs 可用于生物医学成像和 NIR 设备的研究。

AgAuSe QDs(Synonyms: AgAuSe)

AgAuSe QDs Chemical Structure

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生物活性

AgAuSe QDs (AgAuSe) is a near infrared (NIR) fluorescent quantum dots (QDs), with a bright emission from 820 to 1170 nm. AgAuSe QDs can be used for the research in biomedical imaging and NIR devices[1].

体外研究
(In Vitro)

AgAuSe QDs has a bright emission from 820 to 1170 nm and achieved a record absolute photoluminescence quantum yield (PLQY) of 65.3% at 978 nm emission among NIR-II QDs without a toxic element and a long lifetime of 4.58 μs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Yang H, et, al. Colloidal Alloyed Quantum Dots with Enhanced Photoluminescence Quantum Yield in the NIR-II Window. J Am Chem Soc. 2021 Feb 17;143(6):2601-2607.

荧光染料NIR-Thiol dinitrobenzenesulfonate

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荧光染料Dye Reagents NIR-Thiol dinitrobenzenesulfonate;

NIR-Thiol dinitrobenzenesulfonate 是一种可透过细胞的 NIR 荧光硫醇传感器。NIR-Thiol dinitrobenzenesulfonate 在 NIR 区域内同时具有吸收和发射作用。当在 NIR 区域激发时，NIR-Thiol dinitrobenzenesulfonate 对硫醇产生较大的启动 NIR 荧光信号，还能够对活细胞和小鼠中内源性产生的硫醇进行成像。

NIR-Thiol dinitrobenzenesulfonate

NIR-Thiol dinitrobenzenesulfonate Chemical Structure

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生物活性

NIR-Thiol dinitrobenzenesulfonate has both absorption and emission in the NIR region. NIR-Thiol dinitrobenzenesulfonate responds to thiol with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-Thiol dinitrobenzenesulfonate is capable of imaging endogenously produced thiol in living cells and mice[1].

体外研究
(In Vitro)

NIR-Thiol dinitrobenzenesulfonate is highly selective to typical small molecular weight biological thiols (Cys, Hcy, and GSH) over other biorelevant species, such as Phe, Gly, Arg, Lys, Tyr, Leu, glucose, Ser, and Val[1].
To assess the ability of the sensor NIR-Thiol dinitrobenzenesulfonate for NIR imaging of thiols in living cells, the sensor is incubated with living HeLa or Bel 7702 cells, and bright fluorescence is observed. Thus, the sensor appears to be cell membrane permeable and capable of NIR imaging of thiols in living cell. NIR-Thiol dinitrobenzenesulfonate has some prominent features, includinf NIR absorption and emission, rapid response, high sensitivity, excellent selectivity, good cell membrane permeability, and low cytotoxicity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

A different amount (0, 20, 40, or 160 nanomoles) of NIR-Thiol dinitrobenzenesulfonate is injected into the ip cavity of mice. Strong fluorescence is noted for the mice injected with 20 nanomoles of NIR-Thiol dinitrobenzenesulfonate, whereas almost no fluorescence is observed in the control mice without being injected with the sensor. In addition, the mice injected with a higher amount (40 or 160 nanomoles) of NIR-Thiol dinitrobenzenesulfonate provids brighter fluorescence. A very large signal-to-noise contrast ratio (ca. 700-fold enhancement) is observed for the mice injected with 20 nanomoles of NIR-Thiol dinitrobenzenesulfonate. In addition, the signal-to-noise contrast ratio jumped to ca. 2900- or 7400-fold enhancement when the mice are injected with 40 or 160 nanomoles of NIR-Thiol dinitrobenzenesulfonate, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

875.83

Formula

C39H33N5O15S2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Yuan L, et al. A unique approach to development of near-infrared fluorescent sensors for in vivo imaging. J Am Chem Soc. 2012 Aug 15;134(32):13510-23.

荧光染料NIR dye-1

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荧光染料Dye Reagents NIR dye-1;

NIR dye-1 (Compound 1h) 是一种近红外 (NIR) 荧光染料。NIR dye-1 在 NIR 区域具有吸收和发射作用，同时保留了光学可调的羟基。

NIR dye-1

NIR dye-1 Chemical Structure

CAS No. : 1392488-07-1

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生物活性

NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group[1].

体外研究
(In Vitro)

To demonstrate the feasibility of developing water-soluble NIR dyes, NIR dye-1 (Compound 1h) is further synthesized, which bears several water-soluble groups. As expected, dye NIR dye-1 (Compound 1h) is soluble in pure PBS and newborn calf serum (without addition of any co-organic solvent) with a solubility of at least 2 mM in PBS and 3 mM in newborn calf serum[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

543.61

Formula

C26H25NO8S2
CAS 号

1392488-07-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Yuan L, et al. A unique approach to development of near-infrared fluorescent sensors for in vivo imaging. J Am Chem Soc. 2012 Aug 15;134(32):13510-23.